Alpha1-acid glycoprotein, age, and sex in mood disorders

被引：0

作者：

Young, RC

Patel, A

Meyers, BS

Kakuma, T

Alexopoulos, GS

机构：

[1] Cornell Univ, Med Ctr, New York Presbyterian Hosp, Dept Psychiat,Westchester Div, White Plains, NY 10605 USA

[2] Cornell Univ, Weill Med Coll, New York, NY USA

来源：

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY | 1999年 / 7卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Serum alpha(1)-acid glycoprotein (AAG) reportedly can increase with age in the normal population especially among women. In 33 patients with unipolar major depression or bipolar disorder serum AAG was measured by age. The authors noted a positive association with age, particularly in depressed female patients (n = 18; r(s) = 0.61; P < 0.01). The authors discuss implications for drug pharmacokinetics. Investigation of AAG in mood disorders needs to take age and sex into consideration.

引用

页码：331 / 334

页数：4

共 19 条

[1] AGE EFFECTS ON ALPHA-1-ACID GLYCOPROTEIN CONCENTRATION AND IMIPRAMINE PLASMA-PROTEIN BINDING [J].