Phase-sensitive swept-source optical coherence tomography imaging of the human retina with a vertical cavity surface-emitting laser light source

被引：109

作者：

Choi, WooJhon ^{[1
,2
]}

Potsaid, Benjamin ^{[1
,2
,3
]}

Jayaraman, Vijaysekhar ^{[4
]}

Baumann, Bernhard ^{[1
,2
,5
,6
]}

Grulkowski, Ireneusz ^{[1
,2
]}

Liu, Jonathan J. ^{[1
,2
]}

Lu, Chen D. ^{[1
,2
]}

Cable, Alex E. ^{[3
]}

Huang, David ^{[7
]}

Duker, Jay S. ^{[5
,6
]}

Fujimoto, James G. ^{[1
,2
]}

机构：

[1] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA

[2] MIT, Elect Res Lab, Cambridge, MA 02139 USA

[3] Thorlabs Inc, Adv Imaging Grp, Newton, NJ 07860 USA

[4] Praevium Res Inc, Santa Barbara, CA 93111 USA

[5] Tufts Univ, New England Eye Ctr, Boston, MA 02116 USA

[6] Tufts Univ, Tufts Med Ctr, Boston, MA 02116 USA

[7] Oregon Hlth & Sci Univ, Casey Eye Inst, Portland, OR 97239 USA

来源：

OPTICS LETTERS | 2013年 / 38卷 / 03期

关键词：

SPECTRAL/FOURIER DOMAIN OCT; BLOOD-FLOW;

D O I：

10.1364/OL.38.000338

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Despite the challenges in achieving high phase stability, Doppler swept-source/Fourier-domain optical coherence tomography (OCT) has advantages of less fringe washout and faster imaging speeds compared to spectral/Fourier-domain detection. This Letter demonstrates swept-source OCT with a vertical cavity surface-emitting laser light source at 400 kHz sweep rate for phase-sensitive Doppler imaging, measuring pulsatile total retinal blood flow with high sensitivity and phase stability. A robust, simple, and computationally efficient phase stabilization approach for phase-sensitive swept-source imaging is also presented. (C) 2013 Optical Society of America

引用

页码：338 / 340

页数：3

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