Revisiting the Design of Phase III Clinical Trials of Antimalarial Drugs for Uncomplicated Plasmodium falciparum Malaria

被引:9
作者
Borrmann, Steffen [1 ,2 ]
Peto, Tim [3 ]
Snow, Robert W. [4 ,5 ]
Gutteridge, Win [7 ]
White, Nicholas J. [5 ,6 ]
机构
[1] Kenya Govt Med Res Ctr, Wellcome Trust Res Programme, Ctr Geog Med Res Coast, Kilifi, Kenya
[2] Heidelberg Univ, Sch Med, Inst Hyg, Heidelberg, Germany
[3] John Radcliffe Hosp, Nuffield Dept Clin Med, Oxford OX3 9DU, England
[4] Kenya Govt Med Res Ctr, Wellcome Trust Res Programme, Ctr Geog Med, Malaria Publ Hlth & Epidemiol Grp, Nairobi, Kenya
[5] Univ Oxford, Churchill Hosp, Ctr Vaccinol & Trop Med, Oxford, England
[6] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit, Bangkok, Thailand
[7] Med Malaria Venture, Geneva, Switzerland
来源
PLOS MEDICINE | 2008年 / 5卷 / 11期
基金
英国惠康基金;
关键词
D O I
10.1371/journal.pmed.0050227
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1546 / 1552
页数:7
相关论文
共 53 条
  • [1] The challenges of changing national malaria drug policy to artemisinin-based combinations in Kenya
    Amin, Abdinasir A.
    Zurovac, Dejan
    Kangwana, Beth B.
    Greenfield, Joanne
    Otieno, Dorothy N.
    Akhwale, Willis S.
    Snow, Robert W.
    [J]. MALARIA JOURNAL, 2007, 6 (1)
  • [2] [Anonymous], 2003, ASS MON ANT DRUG EFF
  • [3] [Anonymous], 2007, Methods and techniques for clinical trials on antimalarial drug efficacy: genotyping to identify parasite populations
  • [4] [Anonymous], 2000, POINTS CONS SWITCH S
  • [5] Antimalarial dosing regimens and drug resistance
    Barnes, Karen I.
    Watkins, William M.
    White, Nicholas J.
    [J]. TRENDS IN PARASITOLOGY, 2008, 24 (03) : 127 - 134
  • [6] Medicines for Malaria Venture: sustaining antimalarial drug development
    Bathurst, Ian
    Hentschel, Chris
    [J]. TRENDS IN PARASITOLOGY, 2006, 22 (07) : 301 - 307
  • [7] Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar
    Bhattarai, Achuyt
    Ali, Abdullah S.
    Kachur, S. Patrick
    Martensson, Andreas
    Abbas, Ali K.
    Khatib, Rashid
    Al-Mafazy, Abdul-wahiyd
    Ramsan, Mahdi
    Rotllant, Guida
    Gerstenmaier, Jan F.
    Molteni, Fabrizio
    Abdulla, Salim
    Montgomery, Scott M.
    Kaneko, Akira
    Bjorkman, Anders
    [J]. PLOS MEDICINE, 2007, 4 (11) : 1784 - 1790
  • [8] Effects of Plasmodium falciparum parasite population size and patient age on early and late parasitological outcomes of antimalarial treatment in children
    Borrmann, Steffen
    Matsiegui, Pierre-Blaise
    Missinou, Michel Anoumou
    Kremsne, Peter G.
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (05) : 1799 - 1805
  • [9] The use of genotyping in antimalarial clinical trials: a systematic review of published studies from 1995-2005
    Collins, William J.
    Greenhouse, Bryan
    Rosenthal, Philip J.
    Dorsey, Grant
    [J]. MALARIA JOURNAL, 2006, 5 (1)
  • [10] Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria
    Djimdé, AA
    Doumbo, OK
    Traore, O
    Guindo, AB
    Kayentao, K
    Diourte, Y
    Niare-Doumbo, S
    Coulibaly, D
    Kone, AK
    Cissoko, Y
    Tekete, M
    Fofana, B
    Dicko, A
    Diallo, DA
    Wellems, TE
    Kwiatkowski, D
    Plowe, CV
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2003, 69 (05) : 558 - 563