Antimicrobial and Antiviral Activity of Hydrolysable Tannins

被引：240
作者：
Buzzini, Pietro [1 ]
Arapitsas, Panagiotis [2 ]
Goretti, Marta [1 ]
Branda, Eva [1 ]
Turchetti, Benedetta [1 ]
Pinelli, Patrizia [2 ]
Ieri, F. [2 ]
Romani, Annalisa [2 ]
机构：
[1] Univ Perugia, Dept Appl Biol Microbiol, I-06121 Perugia, Italy
[2] Univ Florence, Dept Pharmaceut Sci, I-50121 Florence, Italy
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2008年 / 8卷 / 12期
关键词：
Hydrolysable tannins; ellagitannins; gallotannins; tannic acid; antiviral activity; antibacterial activity; antimycotic activity;
D O I：
10.2174/138955708786140990
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Hydrolysable tannins (HTs), secondary metabolites widely distributed in the plant kingdom, are generally multiple esters of gallic acid with glucose. HTs have been shown to be effective antagonists against viruses, bacteria and eukaryotic microorganisms. The present review examines the antimicrobial and antiviral activity of HTs, the mechanism(s) of action, and some structure-activity relationships.
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页码：1179 / 1187
页数：9
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