Allele frequency comparative study between the two main Egyptian ethnic groups

被引：0

作者：

Taha, Tarek ^{[1
]}

Elzalabany, Sagy ^{[2
]}

Fawzi, Sahar ^{[3
]}

Hisham, Ahmed ^{[3
]}

Amer, Khaled ^{[2
]}

Shaker, Olfat ^{[4
]}

机构：

[1] Egyptian Army Cent Med Labs, Dept Immune Dis, Cairo, Egypt

[2] Egypt Ctr Res & Regenerat Med, Cairo, Egypt

[3] CairoUniversity, Fac Engn, Dept Syst & Biomed Engn, Cairo 12613, Egypt

[4] Cairo Univ, Fac Med, Dept Med Biochem & Mol Biol, Cairo, Egypt

来源：

FORENSIC SCIENCE INTERNATIONAL | 2020年 / 313卷

关键词：

STRs; Population genetics; Allele frequency;

D O I：

10.1016/j.forsciint.2020.110348

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

The study of genetic correlation between ethnic groups, constituting one nation, is an important issue. This work aims to study the correlation between allele frequencies of nine Short Tandem Repeats (STRs) autosomal loci (D3S1358, VWA, FGA, THO1, TPOX, CSF1PO, D5S818, D13S317, and D7S820) for the main two Egyptian ethnic groups, Muslims and Christians, in order to test the hypothesis of a common ancestral for the whole Egyptian population. Each group is represented by a sample of 100 unrelated healthy individuals. The genetic correlation of the two ethnic groups is investigated using alleles' frequencies statistics, forensic efficiency parameters and populations' homogeneity charts. Graphical methods were used to check the harmony between the two ethnic groups. The results support that Egyptian Muslims and Egyptian Christians genetically originate from the same ancestors. (C) 2020 Elsevier B.V. All rights reserved.

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