Comparisons of pathologic and normal skin reactive autoantibodies and the interference phenomenon

被引：3

作者：

Beutner, Ernst H. ^{[1
,2
,3
]}

Grover, Raminder K. ^{[1
,2
]}

Plunkett, Richard W. ^{[1
,2
]}

Lewis, Michelle E. ^{[1
]}

机构：

[1] Beutner Labs Inc, Buffalo, NY 14215 USA

[2] SUNY Buffalo, Sch Med, Dept Microbiol & Immunol, Buffalo, NY 14214 USA

[3] SUNY Buffalo, Sch Med, Dept Dermatol, Buffalo, NY 14214 USA

来源：

CLINICS IN DERMATOLOGY | 2012年 / 30卷 / 04期

关键词：

D O I：

10.1016/j.clindermatol.2012.03.001

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Immunofluorescent serum studies of the roles of the two groups of normal complement-fixing autoantibodies in psoriasis are complicated by the interference phenomenon. Both antibodies have the potential to react in vivo at sites of trauma and in psoriasiform lesions. In serum tests, only one or the other reacts, as demonstrated by immunofluorescent serum tests and absorption studies with isolated stratum corneum antigen. In tests of 15 normal sera, only one consistently reacted with the soluble carbohydrate antigens; the rest consistently reacted with the glycoproteins of the keratin intermediate filaments. This appears to be due to an antibody interference reaction that permits only one of two or more antibodies to react on a given tissue section. (C) 2012 Elsevier Inc. All rights reserved.

引用

页码：447 / 449

页数：3

共 50 条

[31] EFFECTS OF PODOPHYLLIN AND OF COLCHICINE ON NORMAL SKIN, ON CONDYLOMA-ACUMINATUM AND ON VERRUCA-VULGARIS - PATHOLOGIC OBSERVATIONS
KING, LS
SULLIVAN, M
ARCHIVES OF PATHOLOGY, 1947, 43 (04): : 374 - 386
[32] SELF REACTIVE REPERTOIRE OF TIGHT SKIN MOUSE - IMMUNOCHEMICAL AND MOLECULAR CHARACTERIZATION OF ANTI-TOPOISOMERASE-I AUTOANTIBODIES
MURYOI, T
KASTURI, KN
KAFINA, MJ
SAITOH, Y
USUBA, O
PERLISH, JS
FLEISCHMAJER, R
BONA, CA
AUTOIMMUNITY, 1991, 9 (02) : 109 - 117
[33] Nonscarring skin blistering disease and mucosal lesions with IgA autoantibodies reactive with collagen VII and IgG reactivity with laminin γ2
Florea, F.
Torio-Padron, N.
Hashimoto, T.
Sitaru, C.
BRITISH JOURNAL OF DERMATOLOGY, 2012, 167 (04) : 938 - 941
[34] Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin
Hinek, Aleksander
Kim, Hyunjun J.
Wang, Yanting
Wang, Andrew
Mitts, Thomas F.
JOURNAL OF DERMATOLOGICAL SCIENCE, 2014, 75 (03) : 173 - 182
[35] Mediastinal Kaposiform Hemangioendothelioma and Kasabach-Merritt Phenomenon in a Patient with no Skin Changes and a Normal Chest CT
Wallenstein, Matthew B.
Hole, Michael K.
McCarthy, Chad
Fijalkowski, Natalia
Jeng, Michael
Wong, Wendy B.
PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2014, 31 (06) : 563 - 567
[36] Comparisons of gene expression in normal, lesional, and non-lesional psoriatic skin using DNA microarray techniques
Xie, Shaoqiong
Chen, Zhongjian
Wang, Qingliang
Song, Xun
Zhang, Linglin
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2014, 53 (10) : 1213 - 1220
[37] Anti-fibrillin-1 autoantibodies induce activation of normal skin fibroblasts which resembles the scleroderma phenotype.
Zhou, XD
Tan, FK
Wallis, D
Milewicz, DM
Arnett, FC
ARTHRITIS AND RHEUMATISM, 2003, 48 (09): : S351 - S351
[38] The oculocardiac reflex (Dagnini-Aschner phenomenon) - Its use in medicine and psychology - An experimental and comparative study of groups of normal and pathologic subjects
Naccarati, S
ARCHIVES OF NEUROLOGY AND PSYCHIATRY, 1921, 5 (01): : 40 - 57
[39] Determining the extent to which clinically effective treatment, ustekinumab or etanercept, reverses the molecular disease profile of psoriatic skin: Comparisons of lesional, nonlesional, and normal skin
Krueger, J.
Brodmerkel, C.
Li, K.
Suarez-Farinas, M.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2011, 64 (02) : AB7 - AB7
[40] ISOLATION AND IDENTIFICATION OF SOLUBLE SKIN-REACTIVE MEMBRANE ANTIGENS OF MALIGNANT AND NORMAL HUMAN BREAST CELLS
HOLLINSHEAD, AC
JAFFURS, WT
ALPERT, LK
HARRIS, JE
HERBERMAN, RB
CANCER RESEARCH, 1974, 34 (11) : 2961 - 2968

← 1 2 3 4 5 →