Gradient Echo T2-weighted Magnetic Resonance Imaging Revealing Cerebral Microbleeds in A Patient with Microscopic Polyangiitis Complicated by Cerebrovascular Disease

被引：13

作者：

Yamashiro, Kazuo ^{[1
]}

Mori, Akio ^{[1
]}

Shimada, Yoshiaki ^{[1
]}

Furuya, Tsuyoshi ^{[1
]}

Noda, Kazuyuki ^{[1
]}

Urabe, Takao ^{[2
]}

Hattori, Nobutaka ^{[2
]}

Okuma, Yasuyuki ^{[1
]}

机构：

[1] Juntendo Univ, Shizuoka Hosp, Dept Neurol, Izunokunishi, Shizuoka 4102295, Japan

[2] Juntendo Univ, Sch Med, Tokyo 113, Japan

来源：

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | 2012年 / 21卷 / 08期

关键词：

Cerebral hemorrhage; cerebral microbleedsgradient echo T2; weighted imaging; microscopic polyangiitis; HEMORRHAGE; INFARCTION; ANCA;

D O I：

10.1016/j.jstrokecerebrovasdis.2011.04.020

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A 67-year-old woman developed alveolar hemorrhage and was positive for the myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA). She was diagnosed as having probable microscopic polyangiitis (MPA) in accordance with the Japanese criteria. Brain computed tomographic and magnetic resonance imaging (MRI) scans revealed asymptomatic chronic cerebral hemorrhage and white matter lesions. She also later developed thalamic infarction. Gradient echo T2-weighted MRI showed cerebral microbleeds. Cerebral microbleeds in our patient represent bleeding-prone necrotizing vasculitis, which is a characteristic pathologic feature of MPA. Although cerebrovascular disease is not major complication of MPA, cerebral hemorrhage occurs more frequently than ischemic infarction, and it can be critical and fatal. Brain MRIs, including gradient echo T2-weighted imaging, should be performed on patients diagnosed as or suspected of having MPA to assess the risk of cerebral hemorrhage.

引用

页码：904.e7 / 904.e9

页数：3