In Vitro Activities of Amphotericin B, Terbinafine, and Azole Drugs against Clinical and Environmental Isolates of Aspergillus terreus Sensu Stricto

被引:11
作者
Fernandez, Mariana S. [1 ]
Rojas, Florencia D. [1 ]
Cattana, Maria E. [1 ]
Sosa, Maria de los Angeles [1 ]
Iovannitti, Cristina A. [2 ]
Lass-Floerl, Cornelia [3 ]
Giusiano, Gustavo E. [1 ]
机构
[1] Univ Nacl Nordeste, Inst Med Reg, Dept Micol, Resistencia, Argentina
[2] Univ Buenos Aires, Fac Med, CONICET UBA, Ctr Micol,IMPAM, Buenos Aires, DF, Argentina
[3] Med Univ Innsbruck, Dept Hyg Microbiol & Social Med, A-6020 Innsbruck, Austria
关键词
EPIDEMIOLOGIC CUTOFF VALUES; FUNGICIDAL ACTIVITIES; MIC DISTRIBUTIONS; VORICONAZOLE; INFECTIONS; ITRACONAZOLE; ANTIFUNGAL; RESISTANCE; SPP; CLSI;
D O I
10.1128/AAC.00045-15
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The antifungal susceptibilities of 40 clinical and environmental isolates of A. terreus sensu stricto to amphotericin B, terbinafine, itraconazole, and voriconazole were determined in accordance with CLSI document M38-A2. All isolates had itraconazole and voriconazole MICs lower than epidemiologic cutoff values, and 5% of the isolates had amphotericin B MICs higher than epidemiologic cutoff values. Terbinafine showed the lowest MICs. No significant differences were found when MICs of clinical and environmental isolates were compared.
引用
收藏
页码:3619 / 3622
页数:4
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