Diverse Sequence Types of Klebsiella pneumoniae Contribute to the Dissemination of blaNDM-1 in India, Sweden, and the United Kingdom

被引：160
作者：
Giske, Christian G. [1 ]
Froding, Inga [1 ]
Hasan, Chowdhury Mehedi [1 ]
Turlej-Rogacka, Agata [1 ,2 ]
Toleman, Mark [3 ]
Livermore, David [4 ,5 ]
Woodford, Neil [4 ]
Walsh, Timothy R. [3 ,6 ]
机构：
[1] Karolinska Univ Hosp, Karolinska Inst MTC, Stockholm, Sweden
[2] Natl Med Inst, Div Clin Microbiol & Infect Prevent, Warsaw, Poland
[3] Cardiff Univ, Cardiff, S Glam, Wales
[4] Hlth Protect Agcy, Antibiot Resistance Monitoring & Reference Lab, London, England
[5] Univ E Anglia, Norwich Med Sch, Norwich NR4 7TJ, Norfolk, England
[6] Univ Queensland, Clin Res Ctr, Herston, Qld, Australia
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2012年 / 56卷 / 05期
关键词：
ESCHERICHIA-COLI; IDENTIFICATION; CARBAPENEMASES; PCR;
D O I：
10.1128/AAC.06142-11
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Clinical isolates of Klebsiella pneumoniae producing NDM-1 carbapenemase from India (n = 22), the United Kingdom (n = 13), and Sweden (n = 4) were subjected to multilocus sequence typing (MLST), automated repetitive sequence-based PCR (rep-PCR), serotyping, virulence gene screening, and plasmid replicon typing. The most frequently detected MLST sequence types (STs) were ST14 (n = 13; all serotype K2), ST11, ST149, ST231, and ST147. The correlation between MLST and automated rep-PCR was excellent. IncA/C was the most frequently detected plasmid replicon type (n = 14). ST14, ST11, and other successful clones may be important for the dissemination of bla(NDM-1).
引用
收藏
页码：2735 / 2738
页数：4
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