New and developing therapies for atopic dermatitis

被引：43

作者：

Hajar, Tamar ^{[1
]}

Gontijo, Joao Renato Vianna ^{[1
]}

Hanifin, Jon M. ^{[1
]}

机构：

[1] Oregon Hlth & Sci Univ, Dept Dermatol, Portland, OR 97201 USA

来源：

ANAIS BRASILEIROS DE DERMATOLOGIA | 2018年 / 93卷 / 01期

关键词：

Dermatitis; atopic; Eczema; Phosphodiesterase inhibitors; Therapeutics; CYCLIC-AMP-PHOSPHODIESTERASE; SKIN BARRIER; IN-VITRO; DUPILUMAB; MODERATE; ADULTS; DERMATOSES; EXPRESSION; APREMILAST; INHIBITOR;

D O I：

10.1590/abd1806-4841.20187682

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Atopic dermatitis is a common inflammatory skin disease. New understanding in disease pathogenesis has led to a considerable number of promising new drugs in development. New topical agents can be especially helpful for children, providing an alternative to the need for chronic topical corticosteroid use. While many patients with mild or moderate disease can be managed with topical treatments, there are unmet needs for recalcitrant and severe cases. New and developing therapies hold promise for real advances in management of this complex disease.

引用

页码：104 / 107

页数：4

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