Parasitenone, a new epoxycyclohexenone related to gabosine from the marine-derived fungus Aspergillus parasiticus

被引：24
|
作者：
Son, BW [1 ]
Choi, JS
Kim, JC
Nam, KW
Kim, DS
Chung, HY
Kang, JS
Choi, HD
机构：
[1] Pukyong Natl Univ, Dept Chem, Pusan 608737, South Korea
[2] Pukyong Natl Univ, Dept Marine Biol, Pusan 608737, South Korea
[3] Kyungsung Univ, Dept Food Sci & Technol, Pusan, South Korea
[4] Pusan Natl Univ, Coll Pharm, Pusan, South Korea
[5] Pusan Natl Univ, Coll Dent, Pusan, South Korea
[6] Dongeui Univ, Dept Chem, Pusan, South Korea
来源：
JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 05期
关键词：
D O I：
10.1021/np010450k
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Bioassay-guided fractionation of an organic extract of the broth from the marine-derived fungus culture of Aspergillus parasiticus led to the isolation and subsequent structural elucidation of a new gabosine derivative, parasitenone (1), and two known benzyl alcohols, 3-chloro-4,5-dihydroxybenzyl alcohol (2) and gentisyl alcohol (3). The benzyl alcohols (2, 3) were identified as the principal free radical scavenging components. Parasitenone (1) also showed moderate activity in the free radical scavenging assay.
引用
收藏
页码：794 / 795
页数：2
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