Cortical connectivity and sensory coding

被引:399
作者
Harris, Kenneth D. [1 ,2 ]
Mrsic-Flogel, Thomas D. [2 ,3 ]
机构
[1] UCL Inst Neurol, London WC1N 3BG, England
[2] UCL Dept Neurosci Physiol & Pharmacol, London WC1E 6DE, England
[3] Univ Basel, Biozentrum, CH-4056 Basel, Switzerland
基金
英国工程与自然科学研究理事会; 欧洲研究理事会; 英国惠康基金; 美国国家卫生研究院;
关键词
PRIMARY VISUAL-CORTEX; PRIMARY SOMATOSENSORY CORTEX; CALLOSAL PROJECTION NEURONS; INHIBITORY NEURONS; IN-VIVO; PYRAMIDAL NEURONS; AUDITORY-CORTEX; GABAERGIC NEURONS; BARREL CORTEX; LAYER-V;
D O I
10.1038/nature12654
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The sensory cortex contains a wide array of neuronal types, which are connected together into complex but partially stereotyped circuits. Sensory stimuli trigger cascades of electrical activity through these circuits, causing specific features of sensory scenes to be encoded in the firing patterns of cortical populations. Recent research is beginning to reveal how the connectivity of individual neurons relates to the sensory features they encode, how differences in the connectivity patterns of different cortical cell classes enable them to encode information using different strategies, and how feedback connections from higher-order cortex allow sensory information to be integrated with behavioural context.
引用
收藏
页码:51 / 58
页数:8
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