The rapid development of information network has pushed mankind into a "digitalized" and "virtualized" era that information is ubiquitous, and the cultural form of the world has undergone significant changes and has brought new possibilities for the expansion of cultural imperialism. In the information era, the imperialistic cultural transmission is more convenient, the form is more diverse, the nature is more secretive, and the imperceptible influence is increasingly dangerous. In the face of the new challenging situation, China should continue to strengthen its own cultural security system, elevate the cultural soft power, improve the culture utterance right, and enhance the cultural self-confidence.