Breast ultrasound lesions recognition: end-to-end deep learning approaches

被引:79
作者
Yap, Moi Hoon [1 ]
Goyal, Manu [1 ]
Osman, Fatima M. [2 ]
Marti, Robert [3 ]
Denton, Erika [4 ]
Juette, Arne [4 ]
Zwiggelaar, Reyer [5 ]
机构
[1] Manchester Metropolitan Univ, Sch Comp Math & Digital Technol, Fac Sci & Engn, Manchester, Lancs, England
[2] Sudan Univ Sci & Technol, Dept Comp Sci, Khartoum, Sudan
[3] Univ Girona, Comp Vis & Robot Inst, Girona, Spain
[4] Norfolk & Norwich Univ Hosp Fdn Trust, Breast Imaging, Norwich, Norfolk, England
[5] Aberystwyth Univ, Dept Comp Sci, Aberystwyth, Dyfed, Wales
关键词
breast ultrasound; breast lesions recognition; fully convolutional network; semantic segmentation; SEGMENTATION APPROACH; TUMOR SEGMENTATION; IMAGE SEGMENTATION; CLASSIFICATION; PERFORMANCE; TEXTURE; CANCER; US;
D O I
10.1117/1.JMI.6.1.011007
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Multistage processing of automated breast ultrasound lesions recognition is dependent on the performance of prior stages. To improve the current state of the art, we propose the use of end-to-end deep learning approaches using fully convolutional networks (FCNs), namely FCN-AlexNet, FCN-32s, FCN-16s, and FCN-8s for semantic segmentation of breast lesions. We use pretrained models based on ImageNet and transfer learning to overcome the issue of data deficiency. We evaluate our results on two datasets, which consist of a total of 113 malignant and 356 benign lesions. To assess the performance, we conduct fivefold cross validation using the following split: 70% for training data, 10% for validation data, and 20% testing data. The results showed that our proposed method performed better on benign lesions, with a top "mean Dice" score of 0.7626 with FCN-16s, when compared with the malignant lesions with a top mean Dice score of 0.5484 with FCN-8s. When considering the number of images with Dice score >0.5, 89.6% of the benign lesions were successfully segmented and correctly recognised, whereas 60.6% of the malignant lesions were successfully segmented and correctly recognized. We conclude the paper by addressing the future challenges of the work. (C) 2018 Society of Photo-Optical Instrumentation Engineers (SPIE)
引用
收藏
页数:8
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