How to integrate investigative toxicology in the drug discovery pipeline

被引:0
|
作者
Mow, Tomas [1 ]
机构
[1] Novo Nordisk AS, Safety Pharmacol & Exploratory Toxicol, Malov, Denmark
关键词
D O I
10.1016/j.toxlet.2017.07.203
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
ISS_1a-05
引用
收藏
页码:S77 / S77
页数:1
相关论文
共 50 条
  • [1] THE INTEGRATION OF INVESTIGATIVE TOXICOLOGY IN THE DRUG DISCOVERY PROCESS
    DEAN, JH
    OLSON, HM
    BIOLOGY OF THE CELL, 1993, 77 (01) : 3 - 8
  • [2] Optimizing Drug Discovery by Investigative Toxicology: Current and Future Trends
    Beilmann, Mario
    Boonen, Harrie
    Czich, Andreas
    Dear, Gordon
    Hewitt, Philip
    Mow, Limas
    Newham, Peter
    Oinonen, Tea
    Pognan, Francois
    Roth, Adrian
    Valentin, Jean-Pierre
    Van Goethem, Freddy
    Weaver, Richard J.
    Birk, Barbara
    Boyer, Scott
    Caloni, Francesca
    Chen, Alice E.
    Corvi, Raffaella
    Cronin, Mark T. D.
    Daneshian, Manias
    Ewart, Lorna C.
    FitzGerald, Rex E.
    Hamilton, Geraldine A.
    Hartung, Thomas
    Kangas, Joshua D.
    Kramer, Nynke L.
    Leist, Marcel
    Marx, Uwe
    Polak, Sebastian
    Rovida, Costanza
    Testai, Emanuela
    van de Water, Bob
    Vulto, Paul
    Steger-Hartmann, Thomas
    ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2019, 36 (02) : 289 - 313
  • [3] Revolution through genomics in investigative and discovery toxicology
    Rodi, CP
    Bunch, RT
    Curtiss, SW
    Kier, LD
    Cabonce, MA
    Davila, JC
    Mitchell, MD
    Alden, CL
    Morris, DL
    TOXICOLOGIC PATHOLOGY, 1999, 27 (01) : 107 - 110
  • [4] How can we bolster the antifungal drug discovery pipeline?
    Jampilek, Josef
    FUTURE MEDICINAL CHEMISTRY, 2016, 8 (12) : 1393 - 1397
  • [5] Use of Zebrafish in Drug Discovery Toxicology
    Cassar, Steven
    Adatto, Isaac
    Freeman, Jennifer L.
    Gamse, Joshua T.
    Iturria, Inaki
    Lawrence, Christian
    Muriana, Arantza
    Peterson, Randall T.
    Van Cruchten, Steven
    Zon, Leonard I.
    CHEMICAL RESEARCH IN TOXICOLOGY, 2020, 33 (01) : 95 - 118
  • [6] Role of toxicology in drug discovery and development
    Goldstein, RS
    IDEA TO PRODUCT: THE PROCESS, 1996, : 47 - 48
  • [7] Recent Advances in Drug Discovery Toxicology
    Tang, Bowen
    More, Vijay
    INTERNATIONAL JOURNAL OF TOXICOLOGY, 2023, 42 (06) : 535 - 550
  • [8] Exploratory toxicology as an integrated part of drug discovery. Part I: Why and how
    Hornberg, Jorrit J.
    Laursen, Morten
    Brenden, Nina
    Persson, Mikael
    Thougaard, Annemette V.
    Toft, Dorthe B.
    Mow, Tomas
    DRUG DISCOVERY TODAY, 2014, 19 (08) : 1131 - 1136
  • [9] Concept of Drug Metabolism in Drug Discovery Pipeline
    Ahmad, Syed Sayeed
    Kamal, Mohammad A.
    CURRENT DRUG METABOLISM, 2019, 20 (09) : 697 - 700
  • [10] Drug target ontology to classify and integrate drug discovery data
    Yu Lin
    Saurabh Mehta
    Hande Küçük-McGinty
    John Paul Turner
    Dusica Vidovic
    Michele Forlin
    Amar Koleti
    Dac-Trung Nguyen
    Lars Juhl Jensen
    Rajarshi Guha
    Stephen L. Mathias
    Oleg Ursu
    Vasileios Stathias
    Jianbin Duan
    Nooshin Nabizadeh
    Caty Chung
    Christopher Mader
    Ubbo Visser
    Jeremy J. Yang
    Cristian G. Bologa
    Tudor I. Oprea
    Stephan C. Schürer
    Journal of Biomedical Semantics, 8