Protective effects of melatonin on male fertility preservation and reproductive system

被引：50

作者：

Sun, Tie-Cheng ^{[1
,2
,3
]}

Li, Hui-Ying ^{[4
]}

Li, Xiao-Yu ^{[5
]}

Yu, Kun ^{[1
]}

Deng, Shou-Long ^{[6
]}

Tian, Li ^{[2
]}

机构：

[1] China Agr Univ, Coll Anim Sci & Technol, Beijing 100193, Peoples R China

[2] Peking Univ, Int Hosp, Reprod Med Ctr, Beijing 102206, Peoples R China

[3] Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing 100101, Peoples R China

[4] Chinese Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, Beijing 102206, Peoples R China

[5] Guangdong Med Univ, Inst Nephrol, Affiliated Hosp, Zhanjiang 524001, Peoples R China

[6] Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China

来源：

CRYOBIOLOGY | 2020年 / 95卷

关键词：

Melatonin; Membrane receptors; Male fertility preservation; Spermatogonial stem cells (SSCs); INDUCED OXIDATIVE STRESS; TESTOSTERONE SECRETION; SPERM CHARACTERISTICS; TESTICULAR TISSUE; GENE-EXPRESSION; GERM-CELLS; RECEPTORS; CRYOPRESERVATION; APOPTOSIS; EMBRYO;

D O I：

10.1016/j.cryobiol.2020.01.018

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Melatonin is a ubiquitous indoleamine hormone synthesized primarily by the pineal gland. Diverse biological actions of melatonin involve quite complex mechanisms via its membrane receptors. More recently, studies have focused on the role of melatonin in male fertility preservation and male reproductive system. The protective effects of melatonin on immature testicular tissue freshness and activity maintenance and the preservation of sperm and spermatogonial stem cells (SSCs) have attracted considerable attention in recent years. Furthermore, since melatonin has strong antioxidant and anti-apoptotic properties, researchers have examined its potential role in male reproductive system. In this article, recent progress regarding melatonin's effects on male fertility preservation and its potential role is reviewed.

引用

页码：1 / 8

页数：8

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