Protective effects of melatonin on male fertility preservation and reproductive system

被引:50
作者
Sun, Tie-Cheng [1 ,2 ,3 ]
Li, Hui-Ying [4 ]
Li, Xiao-Yu [5 ]
Yu, Kun [1 ]
Deng, Shou-Long [6 ]
Tian, Li [2 ]
机构
[1] China Agr Univ, Coll Anim Sci & Technol, Beijing 100193, Peoples R China
[2] Peking Univ, Int Hosp, Reprod Med Ctr, Beijing 102206, Peoples R China
[3] Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing 100101, Peoples R China
[4] Chinese Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, Beijing 102206, Peoples R China
[5] Guangdong Med Univ, Inst Nephrol, Affiliated Hosp, Zhanjiang 524001, Peoples R China
[6] Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
关键词
Melatonin; Membrane receptors; Male fertility preservation; Spermatogonial stem cells (SSCs); INDUCED OXIDATIVE STRESS; TESTOSTERONE SECRETION; SPERM CHARACTERISTICS; TESTICULAR TISSUE; GENE-EXPRESSION; GERM-CELLS; RECEPTORS; CRYOPRESERVATION; APOPTOSIS; EMBRYO;
D O I
10.1016/j.cryobiol.2020.01.018
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Melatonin is a ubiquitous indoleamine hormone synthesized primarily by the pineal gland. Diverse biological actions of melatonin involve quite complex mechanisms via its membrane receptors. More recently, studies have focused on the role of melatonin in male fertility preservation and male reproductive system. The protective effects of melatonin on immature testicular tissue freshness and activity maintenance and the preservation of sperm and spermatogonial stem cells (SSCs) have attracted considerable attention in recent years. Furthermore, since melatonin has strong antioxidant and anti-apoptotic properties, researchers have examined its potential role in male reproductive system. In this article, recent progress regarding melatonin's effects on male fertility preservation and its potential role is reviewed.
引用
收藏
页码:1 / 8
页数:8
相关论文
共 111 条
[1]  
Aitken RJ, 1999, J REPROD FERTIL, V115, P1
[2]   The chemistry of melatonin's interaction with reactive species [J].
Allegra, M ;
Reiter, RJ ;
Tan, DX ;
Gentile, C ;
Tesoriere, L ;
Livrea, MA .
JOURNAL OF PINEAL RESEARCH, 2003, 34 (01) :1-10
[3]   Melatonin ameliorates bisphenol A-induced biochemical toxicity in testicular mitochondria of mouse [J].
Anjum, Sameya ;
Rahman, Shakilur ;
Maur, Manpreet ;
Ahmad, Firoz ;
Rashid, Hina ;
Ansari, Rizwan Ahmad ;
Raisuddin, Sheikh .
FOOD AND CHEMICAL TOXICOLOGY, 2011, 49 (11) :2849-2854
[4]   Antioxidative effect of melatonin on cryopreserved chicken semen [J].
Appiah, Michael Osei ;
He, Beibei ;
Lu, Wenfa ;
Wang, Jun .
CRYOBIOLOGY, 2019, 89 :90-95
[5]   Association between Maternal Exposure to di(2-ethylhexyl) Phthalate and Reproductive Hormone Levels in Fetal Blood: The Hokkaido Study on Environment and Children's Health [J].
Araki, Atsuko ;
Mitsui, Takahiko ;
Miyashita, Chihiro ;
Nakajima, Tamie ;
Naito, Hisao ;
Ito, Sachiko ;
Sasaki, Seiko ;
Cho, Kazutoshi ;
Ikeno, Tamiko ;
Nonomura, Katsuya ;
Kishi, Reiko .
PLOS ONE, 2014, 9 (10)
[6]  
Assis ID, 2019, CRYOLETTERS, V40, P152
[7]   Exogenous Melatonin Improves Antioxidant Defensein Cucumber Seeds (Cucumis sativus L.) Germinated under Chilling Stress [J].
Balabusta, Marta ;
Szafranska, Katarzyna ;
Posmyk, Malgorzata M. .
FRONTIERS IN PLANT SCIENCE, 2016, 7
[8]   SPERMATOGENESIS FOLLOWING MALE GERM-CELL TRANSPLANTATION [J].
BRINSTER, RL ;
ZIMMERMANN, JW .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (24) :11298-11302
[9]   Redox activation of Nrf2 & NF-κB: A double end sword? [J].
Buelna-Chontal, Mabel ;
Zazueta, Cecilia .
CELLULAR SIGNALLING, 2013, 25 (12) :2548-2557
[10]  
Bustos-Obregon E., 2005, Italian Journal of Anatomy and Embryology, V110, P159