Rapid Decay of Anti-SARS-CoV-2 Antibodies in Persons with Mild Covid-19

被引：832

作者：

Ibarrondo, F. Javier ^{[1
]}

Fulcher, Jennifer A. ^{[1
]}

Yang, Otto O. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2020年 / 383卷 / 11期

基金：

美国国家卫生研究院;

关键词：

CORONAVIRUS;

D O I：

10.1056/NEJMc2025179

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Among 34 volunteers who had recovered from mild Covid-19 illness, antiviral antibodies to the receptor-binding domain of the viral spike protein declined with a mean half-life of approximately 36 days after recovery. Whether these results predict the duration of viral immunity in persons recovering from more severe cases of Covid-19 or those exposed to vaccines is unknown.

引用

页码：1085 / 1087

页数：3

共 5 条

[1] Disappearance of antibodies to SARS-associated coronavirus after recovery [J].

Cao, Wu-Chun ;

Liu, Wei ;

Zhang, Pan-He ;

Zhang, Fang ;

Richardus, Jan H. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (11) :1162-1163

[2] Longitudinal analysis of severe acute respiratory syndrome (SARS) coronavirus-specific antibody in SARS patients [J].

Chang, SC ;

Wang, JT ;

Huang, LM ;

Chen, YC ;

Fang, CT ;

Sheng, WH ;

Wang, JL ;

Yu, CJ ;

Yang, PC .

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2005, 12 (12) :1455-1457

[3] Early maternal separation accelerates the progression of endometriosis in adult mice [J].

Long, Qiqi ;

Liu, Xishi ;

Guo, Sun-Wei .

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2020, 18 (01)

[4]

Stadlbauer Daniel, 2020, Curr Protoc Microbiol, V57, pe100, DOI 10.1002/cpmc.100

[5]

2012, SURG OBES RELAT DIS, V8, pE1002

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