The INO80 chromatin remodeling complex in transcription, replication and repair

被引：147

作者：

Conaway, Ronald C. ^{[1
,2
]}

Conaway, Joan Weliky ^{[1
,2
]}

机构：

[1] Stowers Inst Med Res, Kansas City, MO 64110 USA

[2] Univ Kansas, Med Ctr, Dept Biochem & Mol Biol, Kansas City, KS 66160 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2009年 / 34卷 / 02期

基金：

美国国家卫生研究院;

关键词：

ACTIN-RELATED PROTEINS; UCH37 DEUBIQUITINATING ENZYME; HOMOLOGOUS RECOMBINATION; DNA-BINDING; SACCHAROMYCES-CEREVISIAE; PROMOTER; BREAK; RECRUITMENT; PROTEASOME; SWR1;

D O I：

10.1016/j.tibs.2008.10.010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Ino80 ATPase is a member of the SNF2 family of ATPases and functions as an integral component of a multisubunit ATP-dependent chromatin remodeling complex. Although INO80 complexes from yeast and higher eukaryotes share a common core of conserved subunits, the complexes have diverged substantially during evolution and have acquired new subunits with apparently species-specific functions. Recent studies have shown that the INO80 complex contributes to a wide variety of chromatin-dependent nuclear transactions, including transcription, DNA repair and DNA replication.

引用

页码：71 / 77

页数：7

共 65 条

[1]

ADAMS BS, 1991, NEW BIOL, V3, P1063

[2] Essential dosage-dependent functions of the transcription factor Yin Yang 1 in late embryonic development and cell cycle progression [J].

Affar, E ;

Gay, F ;

Shi, YJ ;

Liu, HF ;

Huarte, M ;

Wu, S ;

Collins, T ;

Li, E ;

Shi, Y .

MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (09) :3565-3581

[3] Genome instability:: a mechanistic view of its causes and consequences [J].

Aguilera, Andres ;

Gomez-Gonzalez, Belen .

NATURE REVIEWS GENETICS, 2008, 9 (03) :204-217

[4] Chromatin remodeling in DNA double-strand break repair [J].

Bao, Yunhe ;

Shen, Xuetong .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2007, 17 (02) :126-131

[5] Redundancy of chromatin remodeling pathways for the induction of the yeast PHO5 promoter in vivo [J].

Barbaric, Slobodan ;

Luckenbach, Tim ;

Schmid, Andrea ;

Blaschke, Dorothea ;

Hoerz, Wolfram ;

Korber, Philipp .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (38) :27610-27621

[6] Endoplasmic reticulum stress induction of the Grp78/BiP promoter: Activating mechanisms mediated by YY1 and its interactive chromatin modifiers [J].

Baumeister, P ;

Luo, SZ ;

Skarnes, WC ;

Sui, GC ;

Seto, E ;

Shi, Y ;

Lee, AS .

MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (11) :4529-4540

[7] Removal of promoter nucleosomes by disassembly rather than sliding in vivo [J].

Boeger, H ;

Griesenbeck, J ;

Strattan, JS ;

Kornberg, RD .

MOLECULAR CELL, 2004, 14 (05) :667-673

[8] Nucleosome retention and the stochastic nature of promoter chromatin remodeling for transcription [J].

Boeger, Hinrich ;

Griesenbeck, Joachim ;

Kornberg, Roger D. .

CELL, 2008, 133 (04) :716-726

[9]

Boyer LA, 2000, BIOESSAYS, V22, P666, DOI 10.1002/1521-1878(200007)22:7<666::AID-BIES9>3.3.CO

[10]

2-P

← 1 2 3 4 5 6 7 →