Facile nucleophilic substitution of 3-tert-butyl-dimethylsilyloxyalk-2-enylphosphonium salts

被引：15

作者：

Lee, PH ^{[1
]}

Cho, M

Han, IS

Kim, S

机构：

[1] Kangweon Natl Univ, Dept Chem, Chunchon 200701, South Korea

[2] Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 38期

关键词：

phosphoniosilylation; nucleophilic substitution; 3-substituted silyl enol ether;

D O I：

10.1016/S0040-4039(99)01438-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Phosphoniosilylation of alpha,beta-enones with TBSOTf and triphenylphosphine at 0 degrees C affords 3-tert-butyldimethylsilyloxyalk-2-enylphosphonium salts, which undergo facile nucleophilic substitution with various nucleophiles to give 3-substituted silyl enol ethers in good yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：6975 / 6978

页数：4

共 20 条

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