COVID-19 associated with encephalomyeloradiculitis and positive anti-aquaporin-4 antibodies: Cause or coincidence?

被引：27

作者：

Correa, Diogo Goulart ^{[1
,2
,3
]}

de Souza Lima, Fabiana Cavalcanti ^{[4
]}

da Cruz Bezerra, Daniel ^{[5
,6
]}

Coutinho, Antonio Carlos Junior ^{[1
,7
]}

Hygino da Cruz, Luiz Celso Junior ^{[1
]}

机构：

[1] Clin Diagnost Imagem CDPI DASA, Dept Radiol, Ave Amer, BR-2640102 Rio De Janeiro, Brazil

[2] Clin Diagnost Imagem CDPI DASA, Dept Radiol, Niteroi, RJ, Brazil

[3] Fed Fluminense Univ, Dept Radiol, Hosp Univ Antonio Pedro, Niteroi, RJ, Brazil

[4] Hosp Univ Pedro Ernesto, Dept Neurol, Rio De Janeiro, Brazil

[5] Hosp Samaritano, Dept Neurol, Rio De Janeiro, Brazil

[6] Hosp Procardiaco, Dept Neurol, Rio De Janeiro, Brazil

[7] Dept Radiol, Nova Iguacu, Brazil

来源：

MULTIPLE SCLEROSIS JOURNAL | 2021年 / 27卷 / 06期

关键词：

COVID-19; encephalomyeloradiculitis; anti-aquaporin-4; antibodies; neuromyelitis optica; brain MRI; spinal MRI;

D O I：

10.1177/1352458520949988

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neurologic complications are being recognized as important outcomes of coronavirus disease 2019 (COVID-19). Pathogenesis is varied and incompletely understood, and may include neuroinvasion, indirect post-infectious neuroinflammation, and cerebrovascular pathologies. We present a case of COVID-19-related encephalomyeloradiculitis with clinical and magnetic resonance imaging characteristics of neuromyelitis optica spectrum disorders that was associated with anti-aquaporin-4 antibodies. Our case suggests post-infectious autoimmunity as a mechanism in at least a subset of patients with COVID-19-related neurologic disease.

引用

页码：973 / 976

页数：4

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