Current Pharmacological Trends on Myricetin

被引:54
作者
Gupta, Gudiya [1 ]
Siddiqui, Mohd Aftab [1 ]
Khan, Mohd Muazzam [1 ]
Ajmal, Mohd [1 ]
Ahsan, Rabiya [1 ]
Rahaman, Md Azizur [2 ]
Ahmad, Md Afroz [1 ]
Arshad, Md [3 ]
Khushtar, Mohammad [1 ]
机构
[1] Integral Univ, Dept Pharmacol, Fac Pharm, Lucknow 226026, Uttar Pradesh, India
[2] Integral Univ, Dept Pharmaceut Chem, Fac Pharm, Lucknow, Uttar Pradesh, India
[3] Aligarh Muslim Univ, Dept Zool, Aligarh, Uttar Pradesh, India
关键词
antioxidants/NO pathways drugs; behavioural pharmacology; toxicology; cardiovascular pharmacology; cancer pharmacology; cancer; CELL-DEATH; FLAVONOIDS; LIPOXYGENASE; SUPPRESSION; INHIBITION; PROTECTION; INJURY;
D O I
10.1055/a-1224-3625
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Myricetin is a member of the group of flavonoids called flavonols. Myricetin is obtained from various fruit, vegetables, tea, berries and red wine. Myricetin is characterized by the pysrogallol Bring, and the more hydroxylated structure is known to be capable for its increased biological properties compared with other flavonols. Myricetin is produced by the Myricaceae, Anacardiaceae, Polygonaceae, Pinaceae and Primulacea families. It is soluble in organic solvent such as ethanol, DMSO (dimethyl sulfoxide), and dimethyl formamide (DMF). It is sparingly soluble in aqueous buffers. Myricetin shows its various pharmacological activities including antioxidant, anti-amyloidogenic, antibacterial, antiviral, antidiabetic, anticancer, anti-inflammatory, anti-epileptic and anti-ulcer. This review article focuses on pharmacological effects of Myricetin on different diseases such as osteoporotic disorder, anti-inflammatory disorder, alzheimer's disease, anti-epileptic, cancer, cardiac disorder, diabetic metabolic disorder, hepatoprotective disorder and gastro protective disorder.
引用
收藏
页码:448 / 454
页数:7
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