CDK inhibitors:: positive and negative regulators of G1-phase progression

被引:5080
作者
Sherr, CJ
Roberts, JM
机构
[1] St Jude Childrens Res Hosp, Howard Hughes Med Inst, Memphis, TN 38105 USA
[2] St Jude Childrens Res Hosp, Dept Tumor Cell Biol, Memphis, TN 38105 USA
[3] Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98104 USA
关键词
D O I
10.1101/gad.13.12.1501
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:1501 / 1512
页数:12
相关论文
共 149 条
[1]   Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27(KIP1) [J].
Aktas, H ;
Cai, H ;
Cooper, GM .
MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (07) :3850-3857
[2]   TRANSFORMING P21(RAS) MUTANTS AND C-ETS-2 ACTIVATE THE CYCLIN D1 PROMOTER THROUGH DISTINGUISHABLE REGIONS [J].
ALBANESE, C ;
JOHNSON, J ;
WATANABE, G ;
EKLUND, N ;
VU, D ;
ARNOLD, A ;
PESTELL, RG .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (40) :23589-23597
[3]   Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts [J].
Alcorta, DA ;
Xiong, Y ;
Phelps, D ;
Hannon, G ;
Beach, D ;
Barrett, JC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (24) :13742-13747
[4]   Cyclin E and c-Myc promote cell proliferation in the presence of p16(INK4a) and of hypophosphorylated retinoblastoma family proteins [J].
Alevizopoulos, K ;
Vlach, J ;
Hennecke, S ;
Amati, B .
EMBO JOURNAL, 1997, 16 (17) :5322-5333
[5]   CYCLIN D1 IS A NUCLEAR-PROTEIN REQUIRED FOR CELL-CYCLE PROGRESSION IN G(1) [J].
BALDIN, V ;
LUKAS, J ;
MARCOTE, MJ ;
PAGANO, M ;
DRAETTA, G .
GENES & DEVELOPMENT, 1993, 7 (05) :812-821
[6]  
Bartkova J, 1997, Prog Cell Cycle Res, V3, P211
[7]   Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) with cyclin A-Cdk2 and cyclin D2-Cdk4 [J].
Blain, SW ;
Montalvo, E ;
Massague, J .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (41) :25863-25872
[8]   A CDC2-LIKE PROTEIN IS INVOLVED IN THE INITIATION OF DNA-REPLICATION IN XENOPUS EGG EXTRACTS [J].
BLOW, JJ ;
NURSE, P .
CELL, 1990, 62 (05) :855-862
[9]   Retinoblastoma protein meets chromatin [J].
Brehm, A ;
Kouzarides, T .
TRENDS IN BIOCHEMICAL SCIENCES, 1999, 24 (04) :142-145
[10]   RADIATION-INDUCED CELL-CYCLE ARREST COMPROMISED BY P21 DEFICIENCY [J].
BRUGAROLAS, J ;
CHANDRASEKARAN, C ;
GORDON, JI ;
BEACH, D ;
JACKS, T ;
HANNON, GJ .
NATURE, 1995, 377 (6549) :552-557