The urea transporter UT-A1 is phosphorylated at serines 486 and 499 downstream of cyclic AMP production

被引:0
|
作者
Thai, Tiffany L. [1 ]
Gumina, Diane L. [1 ]
Ilori, Titilayo O. [1 ]
Klein, Janet D. [1 ]
Blount, Mitsi A. [1 ]
Sands, Jeff M. [1 ]
机构
[1] Emory Univ, Sch Med, Div Renal, Atlanta, GA 30322 USA
来源
FASEB JOURNAL | 2012年 / 26卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:1
相关论文
共 50 条
  • [41] N-LINKED GLYCOSYLATION IS REQUIRED FOR UT-A1 UREA TRANSPORTER TRAFFICKING INTO THE MEMBRANE LIPID RAFT SUBDOMAINS
    Chen, Guangping
    Howe, Ashley G.
    Froehlich, Otto
    Klein, Janet D.
    Sands, Jeff M.
    FASEB JOURNAL, 2011, 25
  • [42] Phosphorylation of UT-A1 on serine 486 correlates with membrane accumulation and urea transport activity in both rat IMCDs and cultured cells
    Klein, Janet D.
    Blount, Mitsi A.
    Frohlich, Otto
    Denson, Chad E.
    Tan, Xiaoxiao
    Sim, Jae H.
    Martin, Christopher F.
    Sands, Jeff M.
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2010, 298 (04) : F935 - F940
  • [43] Cloning and characterization of the human urea transporter UT-A1 and mapping of the human Slc14a2 gene
    Bagnasco, SM
    Peng, T
    Janech, MG
    Karakashian, A
    Sands, JM
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2001, 281 (03) : F400 - F406
  • [44] Vasopressin increases plasma membrane accumulation of the UT-A1 urea transporter in rat inner medullary collecting ducts
    Klein, JD
    Froehlich, O
    Smith, TD
    Sands, JM
    FASEB JOURNAL, 2006, 20 (05): : A1218 - A1218
  • [45] Vasopressin-Regulated Phosphorylation of Urea Transporter Proteins, UT-A1 and UT-A3, in Rat Inner Medullary Collecting Duct (IMCD)
    Hwang, Shelly
    Chou, C-L
    Yu, M-J
    Rinschen, M.
    Gunaratne, R.
    Pisitkun, T.
    Hoffert, J. D.
    Knepper, M. A.
    FASEB JOURNAL, 2010, 24
  • [46] Depolymerization of cortical actin inhibits UT-A1 urea transporter endocytosis but promotes forskolin-stimulated membrane trafficking
    Xu, Gang
    Su, Hua
    Carter, Conner B.
    Froehlich, Otto
    Chen, Guangping
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2012, 302 (07): : C1012 - C1018
  • [47] MDM2 E3 ubiquitin ligase mediates UT-A1 urea transporter ubiquitination and degradation
    Chen, Guangping
    Huang, Haidong
    Frohlich, Otto
    Yang, Yuan
    Klein, Janet D.
    Price, S. Russ
    Sands, Jeff M.
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2008, 295 (05) : F1528 - F1534
  • [48] Lack of PKCα leads to Altered Urea Transporter UT-A1 and Aquaporin-2 in Angiotensin II-induced Hypertension
    Thai, Tiffany L.
    Klein, Janet D.
    Sands, Jeff M.
    FASEB JOURNAL, 2011, 25
  • [49] 97-and 117-kDa forms of collecting duct urea transporter UT-A1 are due to different states of glycosylation
    Bradford, AD
    Terris, JM
    Ecelbarger, CA
    Klein, JD
    Sands, JM
    Chou, CL
    Knepper, MA
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2001, 281 (01) : F133 - F143
  • [50] Internalization of UT-A1 urea transporter is dynamin dependent and mediated by both caveolae- and clathrin-coated pit pathways
    Huang, Haidong
    Feng, Xiuyan
    Zhuang, Jieqiu
    Froehlich, Otto
    Klein, Janet D.
    Cai, Hui
    Sands, Jeff M.
    Chen, Guangping
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2010, 299 (06) : F1389 - F1395