Crystal structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase complexed with 17 beta-estradiol

被引：141
|
作者：
Azzi, A
Rehse, PH
Zhu, DW
Campbell, RL
Labrie, F
Lin, SX
机构：
[1] CHU LAVAL,MRC,GRP MOL ENDOCRINOL,QUEBEC CITY,PQ G1V 4G2,CANADA
[2] UNIV LAVAL,QUEBEC CITY,PQ G1V 4G2,CANADA
来源：
NATURE STRUCTURAL BIOLOGY | 1996年 / 3卷 / 08期
关键词：
D O I：
10.1038/nsb0896-665
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Estrogenic 17 beta-hydroxysteroid dehydrogenase may promote tumour growth in some breast carcinomas. The 2.3 Angstrom structure of the human enzyme Complexed with 17 beta-estradiol gives insight into the specificity of substrate binding.
引用
收藏
页码：665 / 668
页数：4
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