Photochemical properties of water-soluble fluorinated zinc phthalocyanines and their photocytotoxicity against HeLa cells

被引:0
作者
Fukushima, K [1 ]
Tabata, K [1 ]
Okura, I [1 ]
机构
[1] Tokyo Inst Technol, Dept Bioengn, Midori Ku, Yokohama, Kanagawa 226, Japan
关键词
fluorinated zinc; phthalocyanine; photodynamic therapy;
D O I
10.1002/(SICI)1099-1409(199805/06)2:3<219::AID-JPP66>3.0.CO;2-G
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Three types of amphiphilic water-soluble fluorinated zinc phthalocyanines are characterized. They have absorption bands at long wavelength, which cause greater penetration depth of a tissue. The uptake and photodynamic activity of the phthalocyanines against HeLa cells were measured, showing that the phthalocyanines exhibited higher photodynamic activities than zinc tetrasulfonated phthalocyanine. (C) 1998 John Wiley & Sons, Ltd.
引用
收藏
页码:219 / 222
页数:4
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