Synthesis of various glycopolymer architectures via RAFT polymerization: From block copolymers to stars

被引：144
作者：
Bernard, J [1 ]
Hao, XJ [1 ]
Davis, TP [1 ]
Barner-Kowollik, C [1 ]
Stenzel, MH [1 ]
机构：
[1] Univ New S Wales, CAMD, Sch Engn & Ind Chem, Sydney, NSW 2052, Australia
来源：
BIOMACROMOLECULES | 2006年 / 7卷 / 01期
关键词：
D O I：
10.1021/bm0506086
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Well-defined linear poly(acryloyl glucosamine) (PAGA) exhibiting molar masses ranging from 3 to 120 K and low polydispersities have been prepared via reversible addition-fragmentation chain transfer polymerization (RAFT) in aqueous solution without recourse to protecting group chemistry. The livingness of the process was further demonstrated by successfully chain-extending one of these polymers with N-isopropylacrylamide affording narrow dispersed thermosensitive diblocks. This strategy of polymerization was finally extended to the preparation of glycopolymer stars from Z designed non-water-soluble trifunctional RAFT agent. After the growth of very short blocks of poly(hydroxyethyl acrylate) <(DP)over bar (nbranch)> = 10), AGA was polymerized in aqueous solution in a controlled manner affording well-defined 3-arm glycopolymer stars.
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页码：232 / 238
页数：7
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