Otogenic Lateral Sinovenous Thrombosis in Children: A Case Series from a Single Centre and Narrative Review

被引：5

作者：

Trapani, Sandra ^{[1
]}

Stivala, Micol ^{[2
]}

Lasagni, Donatella ^{[2
]}

Rosati, Anna ^{[3
]}

Indolfi, Giuseppe ^{[4
]}

机构：

[1] Meyer Childrens Univ Hosp, Dept Hlth Sci, Paediat Unit, Viale Pieraccini 24, I-50139 Florence, Italy

[2] Meyer Childrens Hosp, Paediat Unit, Viale Pieraccini 24, I-50139 Florence, Italy

[3] Meyer Childrens Hosp, Child Neurol Unit, Viale Pieraccini 24, I-50139 Florence, Italy

[4] Meyer Childrens Hosp, Prof NEUROFARBA Dept, Viale Pieraccini 24, I-50139 Florence, Italy

来源：

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | 2020年 / 29卷 / 10期

关键词：

Otomastoiditis; Children; Otogenic sinovenous thrombosis; Headache; Papilledema; VENOUS SINUS THROMBOSIS; ARTERIAL ISCHEMIC-STROKE; OTITIS-MEDIA; PROTHROMBOTIC FACTORS; MANAGEMENT; COMPLICATIONS; PREVENTION; EXPERIENCE; DIAGNOSIS; RISK;

D O I：

10.1016/j.jstrokecerebrovasdis.2020.105184

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Aim: We aimed to describe otogenic lateral sinovenous thrombosis (OLST), a rare, potentially life-threatening complication of otomastoiditis. Methods: Children diagnosed with OLST in a tertiary-care Hospital from 2014 to 2019 was retrospectively selected. Clinical and radiological features, timing of diagnosis, treatment and outcome are reported. Results: Seven children (5 males) were studied. Fever and neurological symptoms (headache, lethargy, diplopia, dizziness and papilledema) were always present. Otalgia and/or otorrhea were found in 6 children; none had signs of mastoiditis. Diagnosis was reached after 7 days (median) from clinical onset. Brain CT-scan was performed in 5 children being diagnostic for 3. Venography-MRI detected OLST and mastoiditis in all cases without parenchymal lesions. Treatment was based on intravenous rehydration, antibiotic and low-molecular weight heparin; acetazolamide was added in 3 children. Mastoidectomy and ventriculoperitoneal-shunting were selectively performed. Patients were discharged after 26 days (median). Follow-up neuroimaging showed sinus recanalization after a median time of 6 months. Conclusion: A multidisciplinary approach is needed to optimize diagnostic-therapeutic protocols of pediatric OLST.

引用

页数：10

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