Unusual duodenal presentation of leishmaniasis

被引:15
作者
Alvarez-Nebreda, ML
Alvarez-Fernández, E
Rada, S
Brañas, F
Marañón, E
Vidán, MT
Serra-Rexach, JA
机构
[1] Hosp Gen Univ Gregorio Maranon, Dept Geriatr, Madrid 28007, Spain
[2] Hosp Gen Univ Gregorio Maranon, Dept Pathol, Madrid, Spain
关键词
D O I
10.1136/jcp.2005.027029
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
This case report describes an atypical case of duodenal leishmaniasis in an elderly patient not infected with human immunodeficiency virus. Investigation of this 84 year old woman with a constitutional syndrome and dysphagia revealed anaemia of chronic disorder, a high erythrocyte sedimentation rate, and polyclonal hypergammaglobulinaemia. Abdominal ultrasonography revealed thickening of the stomach wall, which was seen to be inflamed during gastroscopy. Duodenal histology revealed numerous leishmania amastigotes within macrophages. This was confirmed by bone marrow biopsy and leishmania serology. This case report stresses the importance of atypical symptoms and the unusual location of visceral leishmaniasis, not only in immunodepressed patients, but also in elderly immunocompetent patients.
引用
收藏
页码:1321 / 1322
页数:2
相关论文
共 10 条
[1]   Duodenal leishmaniasis diagnosed by biopsy in two HIV-positive patients [J].
Alonso, MJ ;
Munoz, E ;
Picazo, A ;
Abad, MM ;
Gomez, F ;
Roldan, M ;
Laguna, F ;
Paz, JI ;
LopezBravo, A .
PATHOLOGY RESEARCH AND PRACTICE, 1997, 193 (01) :43-47
[2]   Human leishmaniasis: Clinical, diagnostic, and chemotherapeutic developments in the last 10 years [J].
Berman, JD .
CLINICAL INFECTIOUS DISEASES, 1997, 24 (04) :684-703
[3]   Treatment of visceral leishmaniasis in HIV-infected patients:: a randomized trial comparing meglumine antimoniate with amphotericin B [J].
Laguna, F ;
López-Vélez, R ;
Pulido, F ;
Salas, A ;
Torre-Cisneros, J ;
Torres, E ;
Medrano, FJ ;
Sanz, J ;
Picó, G ;
Gómez-Rodrigo, J ;
Pasquau, J ;
Alvar, J .
AIDS, 1999, 13 (09) :1063-1069
[4]   GASTROINTESTINAL LEISHMANIASIS IN HUMAN IMMUNODEFICIENCY VIRUS-INFECTED PATIENTS - REPORT OF 5 CASES AND REVIEW [J].
LAGUNA, F ;
GARCIASAMANIEGO, J ;
SORIANO, V ;
VALENCIA, E ;
REDONDO, C ;
ALONSO, MJ ;
GONZALEZLAHOZ, JM .
CLINICAL INFECTIOUS DISEASES, 1994, 19 (01) :48-53
[5]   AN UNUSUAL GASTROINTESTINAL PRESENTATION OF LEISHMANIASIS [J].
MCBRIDE, MO ;
FISHER, M ;
SKINNER, CJ ;
GOLDEN, R ;
MAIN, J .
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 1995, 27 (03) :297-298
[6]   Prevalence of and factors associated with visceral leishmaniasis in human immunodeficiency virus type 1-infected patients in southern Spain [J].
Pineda, JA ;
Gallardo, JA ;
Macías, J ;
Delgado, J ;
Regórdán, C ;
Morillas, F ;
Relimpio, F ;
Martín-Sánchez, J ;
Sánchez-Quijano, A ;
Leal, M ;
Lissen, E .
JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (09) :2419-2422
[7]   Visceral leishmaniasis in human immunodeficiency virus (HIV)-infected and non-HIV-infected patients -: A comparative study [J].
Pintado, V ;
Martín-Rabadán, P ;
Rivera, ML ;
Moreno, S ;
Bouza, E .
MEDICINE, 2001, 80 (01) :54-73
[8]  
Reus S, 1999, Enferm Infecc Microbiol Clin, V17, P515
[9]   HIV and Leishmania coinfection:: A review of 91 cases with focus on atypical locations of Leishmania [J].
Rosenthal, E ;
Marty, P ;
del Giudice, P ;
Pradier, C ;
Ceppi, C ;
Gastaut, JA ;
Le Fichoux, Y ;
Cassuto, JP .
CLINICAL INFECTIOUS DISEASES, 2000, 31 (04) :1093-1095
[10]  
RUDI J, 1993, CLIN INVESTIGATOR, V71, P616, DOI 10.1007/BF00184486