Cadherins and their connections: adhesion junctions have broader functions

被引：254

作者：

Steinberg, MS ^{[1
]}

McNutt, PM ^{[1
]}

机构：

[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 05期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0955-0674(99)00027-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cadherins - a family of cell-cell adhesion molecules - are linked to the actin cytoskeleton via intervening proteins. Recent results address molecular explanations for observed cadherin behavior, point to signals that regulate adhesion by modulating elements of the cadherin-associated complex, challenge the belief that different cadherins generally cannot cross-adhere, and highlight instructive roles for cadherins in cell signaling and differentiation.

引用

页码：554 / 560

页数：7

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