One-pot synthesis of 2-amino-3-cyanopyridine derivatives under solvent-free conditions

被引：24

作者：

Ghorbani-Vaghei, Ramin ^{[1
]}

Toghraei-Semiromi, Zahra ^{[1
]}

Karimi-Nami, Rahman ^{[2
]}

机构：

[1] Bu Ali Sina Univ, Dept Organ Chem, Fac Chem, Hamadan 65174, Iran

[2] Univ Tehran, Sch Chem, Univ Coll Sci, Tehran, Iran

来源：

COMPTES RENDUS CHIMIE | 2013年 / 16卷 / 12期

关键词：

2-Amino-3-cyanopyridine; Multicomponent reaction; Aldehyde; Ketone; Malononitrile; Ammonium acetate; Solvent-free; TBBDA; PBBS; MILD; N,N,N',N'-TETRABROMOBENZENE-1,3-DISULFONYLAMIDE; INHIBITORS; DISCOVERY; REAGENTS;

D O I：

10.1016/j.crci.2013.06.006

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of 2-amino-3-cyanopyridines were obtained from aryl aldehydes, substituted acetophenones, malononitrile and ammonium acetate in good to excellent yields by proceeding through a simple, mild and efficient procedure utilizing N,N,N ',N '-tetra-bromobenzene-1,3-disulfonamide [TBBDA and poly(N-bromo-N-ethylbenzene-1,3-disulfonamide) IPBBS] as catalysts. (C) 2013 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：1111 / 1117

页数：7

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