Nigral endothelial dysfunction, homocysteine, and Parkinson's disease

被引：112
作者：
Müller, T
Werne, B
Fowler, B
Kuhn, W
机构：
[1] Ruhr Univ Bochum, St Josef Hosp, Dept Neurol, D-44791 Bochum, Germany
[2] Univ Childrens Hosp, Basel, Switzerland
来源：
LANCET | 1999年 / 354卷 / 9173期
关键词：
D O I：
10.1016/S0140-6736(99)01660-8
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We found increased levels of atherosclerosis-inducing homocysteine in parkinsonian patients with long-term application of levodopa compared with previously untreated parkinsonian patients and controls. We conclude that antiparkinsonian treatment with levodopa promotes occurrence of vascular disease in Parkinson's disease.
引用
收藏
页码：126 / 127
页数：2
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