Developmental regulation of dendritic cell function

被引：50

作者：

Lane, PJL

Brocker, T

机构：

[1] Max Planck Inst Immunobiol, D-79108 Freiburg, Germany

[2] Univ Birmingham, Sch Med, Dept Immunol & Infect, MRC,Ctr Immune Regulat, Birmingham B15 2TT, W Midlands, England

来源：

CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0952-7915(99)80049-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

1998 saw key advances in our understanding of the molecular mechanisms whereby immature dendritic cells recognise foreign pathogens:in tissues and are induced to migrate to secondary lymphoid organs. In particular, there have been some key insights into how dendritic cells subsequently direct the evolution of immune responses by differential expression of co-stimulatory molecules.

引用

页码：308 / 313

页数：6

共 43 条

[41] T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching [J].