Ice-templated hydrogels based on chitosan with tailored porous morphology

被引：68
作者：
Dinu, Maria Valentina [1 ]
Pradny, Martin [2 ]
Dragan, Ecaterina Stela [1 ]
Michalek, Jiri [2 ]
机构：
[1] Petru Poni Inst Macromol Chem, RO-700487 Iasi, Romania
[2] Acad Sci Czech Republ, Inst Macromol Chem, Prague 6, Czech Republic
来源：
CARBOHYDRATE POLYMERS | 2013年 / 94卷 / 01期
关键词：
Chitosan; Ice-templated hydrogels; Morphology; Unidirectional freezing; 2-HYDROXYETHYL METHACRYLATE; CRYOGELS; POLYACRYLAMIDE; PHASE;
D O I：
10.1016/j.carbpol.2013.01.084
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Preparation and morphological characterization of some novel hydrogels based on chitosan (CS) with porous structure tailored by ice-templating and porogen leaching are presented in the paper. Poly(methylmethacrylate) (PMMA), as fractionated particles, has been used as polymer porogen. The influence of the mesh of the fractionated PMMA particles, the weight ratio between CS and fractionated PMMA particles, and the speed of the crystallization, on the internal morphology of the hydrogels have been deeply investigated. The morphology of the obtained hydrogels was observed by scanning electron microscopy (SEM). As a function of the synthesis conditions, hydrogels with a heterogeneous morphology consisting of randomly and evenly distributed polyhedral pores, or with an oriented structure, which has microchanneled structures arranged along the freezing direction, were generated. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：170 / 178
页数：9
相关论文
共 37 条
[1]  
Aranaz I., 2009, CURRENT CHEM BIOL, V3, P203, DOI [10.2174/2212796810903020203, 10.2174/187231309788166415]
[2]   Responsive polymers in controlled drug delivery [J].
Bajpai, A. K. ;
Shukla, Sandeep K. ;
Bhanu, Smitha ;
Kankane, Sanjana .
PROGRESS IN POLYMER SCIENCE, 2008, 33 (11) :1088-1118
[3]   Bilirubin recognition via molecularly imprinted supermacroporous cryogels [J].
Baydemir, Goezde ;
Bereli, Nilay ;
Andac, Muege ;
Say, Ridvan ;
Galaev, Igor Yu ;
Denizli, Adil .
COLLOIDS AND SURFACES B-BIOINTERFACES, 2009, 68 (01) :33-38
[4]   An infrared investigation in relation with chitin and chitosan characterization [J].
Brugnerotto, J ;
Lizardi, J ;
Goycoolea, FM ;
Argüelles-Monal, W ;
Desbrières, J ;
Rinaudo, M .
POLYMER, 2001, 42 (08) :3569-3580
[5]   Fabrication and characterization of novel macroporous cellulose-alginate hydrogels [J].
Chang, Chunyu ;
Duan, Bo ;
Zhang, Lina .
POLYMER, 2009, 50 (23) :5467-5473
[6]   Freezing as a path to build macroporous structures: Superfast responsive polyacrylamide hydrogels [J].
Dinu, M. Valentina ;
Ozmen, M. Murat ;
Dragan, E. Stela ;
Okay, Oguz .
POLYMER, 2007, 48 (01) :195-204
[7]   Composite IPN ionic hydrogels based on polyacrylamide and dextran sulfate [J].
Dinu, Maria Valentina ;
Perju, Maria Marinela ;
Dragan, Ecaterina Stela .
REACTIVE & FUNCTIONAL POLYMERS, 2011, 71 (08) :881-890
[8]   Porous Semi-Interpenetrating Hydrogel Networks Based on Dextran and Polyacrylamide With Superfast Responsiveness [J].
Dinu, Maria Valentina ;
Perju, Maria Marinela ;
Dragan, Ecaterina Stela .
MACROMOLECULAR CHEMISTRY AND PHYSICS, 2011, 212 (03) :240-251
[9]   Redox-Responsive Degradable PEG Cryogels as Potential Cell Scaffolds in Tissue Engineering [J].
Dispinar, Tugba ;
Van Camp, Wim ;
De Cock, Liesbeth J. ;
De Geest, Bruno G. ;
Du Prez, Filip E. .
MACROMOLECULAR BIOSCIENCE, 2012, 12 (03) :383-394
[10]   Preparation and characterization of IPN composite hydrogels based on polyacrylamide and chitosan and their interaction with ionic dyes [J].
Dragan, Ecaterina Stela ;
Perju, Maria Marinela ;
Dinu, Maria Valentina .
CARBOHYDRATE POLYMERS, 2012, 88 (01) :270-281
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