Synthesis, antimicrobial and antioxidant activities of 5-((2-oxo-2H-chromen-7-yloxy)methyl)-1,3,4-thiadiazol-2(3H)-one derived from umbelliferone

被引：15

作者：

Al-Amiery, Ahmed A. ^{[1
]}

Al-Temimi, Ali A. ^{[1
]}

Sulaiman, Ghassan M. ^{[1
]}

Aday, Hamdan A. ^{[1
]}

Kadhum, Abdul Amir Hassan ^{[2
]}

Mohamad, Abu Bakar ^{[2
]}

机构：

[1] Univ Technol Baghdad, Dept Appl Sci, Div Biotechnol, Baghdad 10066, Iraq

[2] Univ Kebangsaan Malaysia, Dept Chem & Proc Engn, Bangi 43000, Malaysia

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2013年 / 48卷 / 06期

关键词：

antimicrobial; antioxidant; 1,3,4-thiadiazole; thiosemicarbazide; umbelliferone; ANTIFUNGAL; COUMARIN; DERIVATIVES; COMPLEXES;

D O I：

10.1007/s10600-013-0436-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

5-((2-Oxo-2H-chromen-7-yloxy)methyl)-1,3,4-thiadiazol-2(3H)-one was synthesized and characterized by FT-IR and NMR spectra in addition to elemental analysis. The prepared compound shows considerable antibacterial and antifungal activity. The free radical scavenging activity of the synthesized compound was screened for in vitro antioxidant activity.

引用

页码：950 / 954

页数：5

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