The Choice Between Advanced Therapies for Parkinson's Disease Patients: Why, What, and When?

被引：49

作者：

Dijk, Joke M. ^{[1
]}

Espay, Alberto J. ^{[2
]}

Katzenschlager, Regina ^{[3
,4
]}

de Bie, Rob M. A. ^{[1
]}

机构：

[1] Univ Amsterdam, Amsterdam UMC, Dept Neurol, Amsterdam Neurosci, Meibergdreef 9, Amsterdam, Netherlands

[2] Univ Cincinnati, James J & Joan A Gardner Family Ctr Parkinsons Di, Dept Neurol, Cincinnati, OH USA

[3] Donauspital, Dept Neurol, Vienna, Austria

[4] Karl Landsteiner Inst Neuroimmunol & Neurodegener, Vienna, Austria

来源：

JOURNAL OF PARKINSONS DISEASE | 2020年 / 10卷

基金：

美国国家卫生研究院;

关键词：

Parkinson's disease; deep brain stimulation; external infusion pumps; parenteral infusions; carbidopa; levodopa; drug combination; apomorphine; review literature; DEEP-BRAIN-STIMULATION; CONTINUOUS SUBCUTANEOUS APOMORPHINE; LEVODOPA/CARBIDOPA INTESTINAL GEL; SUBTHALAMIC NUCLEUS; INFUSION; MOTOR; NEUROSTIMULATION; MANAGEMENT; CONSENSUS; LINE;

D O I：

10.3233/JPD-202104

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

When oral dopaminergic medication falls short in the treatment of Parkinson's disease, patients are left with motor response fluctuations and dyskinesias that may have a large impact on functioning in daily life. They may benefit from one of the currently available advanced treatments, namely deep brain stimulation, continuous levodopa-carbidopa intestinal gel, and continuous subcutaneous apomorphine infusion. The indication, choice between the separate advanced treatments and the timing can be challenging and will be discussed against the background of the progressive nature of the disease, the heterogeneity of disease manifestation and variable patient characteristics.

引用

页码：S65 / S73

页数：9

共 52 条

[1] Economic Evaluation of Interventions in Parkinson's Disease: A Systematic Literature Review [J].

Afentou, Nafsika ;

Jarl, Johan ;

Gerdtham, Ulf-G ;

Saha, Sanjib .

MOVEMENT DISORDERS CLINICAL PRACTICE, 2019, 6 (04) :282-290

[2] Developing consensus among movement disorder specialists on clinical indicators for identification and management of advanced Parkinson's disease: a multi-country Delphi-panel approach [J].

Antonini, Angelo ;

Stoessl, A. Jon ;

Kleinman, Leah S. ;

Skalicky, Anne M. ;

Marshall, Thomas S. ;

Sail, Kavita R. ;

Onuk, Koray ;

Odin, Per Lars Anders .

CURRENT MEDICAL RESEARCH AND OPINION, 2018, 34 (12) :2063-2073

[3] Apomorphine and levodopa infusion for motor fluctuations and dyskinesia in advanced Parkinson disease [J].

Antonini, Angelo ;

Nitu, Bianca .

JOURNAL OF NEURAL TRANSMISSION, 2018, 125 (08) :1131-1135

[4] Rescue Levodopa/Carbidopa Intestinal Gel for Secondary Deep Brain Stimulation Failure [J].

Bautista, Juan Miguel Pilar ;

Oyama, Genko ;

Nuermaimaiti, Maierdanjiang ;

Sekimoto, Satoko ;

Sasaki, Fuyuko ;

Hatano, Taku ;

Nishioka, Kenya ;

Ito, Masanobu ;

Umemura, Atsushi ;

Ishibashi, Yuji ;

Shimo, Yasushi ;

Hattori, Nobutaka .

JOURNAL OF MOVEMENT DISORDERS, 2020, 13 (01) :57-61

[5] Delayed Gastric Emptying in Advanced Parkinson Disease Correlation With Therapeutic Doses [J].

Bestetti, Alberto ;

Capozza, Antonella ;

Lacerenza, Marco ;

Manfredi, Luigi ;

Mancini, Francesca .

CLINICAL NUCLEAR MEDICINE, 2017, 42 (02) :83-87

[6] Long-term Apomorphine Infusion Users Versus Short-term Users: An International Dual-center Analysis of the Reasons for Discontinuing Therapy [J].

Bhidayasiri, Roongroj ;

Phokaewvarangkul, Onanong ;

Boonpang, Kamolwan ;

Boonmongkol, Thanatat ;

Thongchuem, Yuwadee ;

Kantachadvanich, Nitinan ;

Garcia Ruiz, Pedro J. .

CLINICAL NEUROPHARMACOLOGY, 2019, 42 (05) :172-178

[7] Effective Delivery of Apomorphine in the Management of Parkinson Disease: Practical Considerations for Clinicians and Parkinson Nurses [J].

Bhidayasiri, Roongroj ;

Chaudhuri, K. Ray ;

LeWitt, Peter ;

Martin, Anne ;

Boonpang, Kamolwan ;

van Laar, Teus .

CLINICAL NEUROPHARMACOLOGY, 2015, 38 (03) :89-103

[8] 3-Tesla MRI of deep brain stimulation patients: safety assessment of coils and pulse sequences [J].

Boutet, Alexandre ;

Hancu, Ileana ;

Saha, Utpal ;

Crawley, Adrian ;

Xu, David S. ;

Ranjan, Manish ;

Hlasny, Eugen ;

Chen, Robert ;

Foltz, Warren ;

Sammartino, Francesco ;

Coblentz, Ailish ;

Kucharczyk, Walter ;

Lozano, Andres M. .

JOURNAL OF NEUROSURGERY, 2020, 132 (02) :586-594

[9] Directional steering A novel approach to deep brain stimulation [J].

Contarino, M. Fiorella ;

Bour, Lo J. ;

Verhagen, Rens ;

Lourens, Marcel A. J. ;

de Bie, Rob M. A. ;

van den Munckhof, Pepijn ;

Schuurman, P. R. .

NEUROLOGY, 2014, 83 (13) :1163-1169

[10] 24-hour levodopa-carbidopa intestinal gel may reduce troublesome dyskinesia in advanced Parkinson's disease [J].

Cruse, Belinda ;

Morales-Briceno, Hugo ;

Chang, Florence C. F. ;

Mahant, Neil ;

Ha, Ainhi D. ;

Kim, Samuel D. ;

Wolfe, Nigel ;

Kwan, Vu ;

Tsui, David S. ;

Griffith, Jane M. ;

Galea, Donna ;

Fung, Victor S. C. .

NPJ PARKINSONS DISEASE, 2018, 4

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