Exercise in the Metabolic Syndrome

被引：93

作者：

Golbidi, Saeid ^{[1
]}

Mesdaghinia, Azam ^{[2
]}

Laher, Ismail ^{[1
]}

机构：

[1] Univ British Columbia, Fac Med, Dept Anesthesiol Pharmacol & Therapeut, Vancouver, BC V6T 1Z3, Canada

[2] Kashan Univ Med Sci & Hlth Serv, Physiol Res Ctr, Kashan 87155111, Iran

来源：

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY | 2012年 / 2012卷

关键词：

TUMOR-NECROSIS-FACTOR; HUMAN SKELETAL-MUSCLE; ANGIOTENSIN-ALDOSTERONE SYSTEM; VASCULAR SUPEROXIDE-PRODUCTION; SALT-SENSITIVE HYPERTENSION; INSULIN-RESISTANCE-SYNDROME; EPICARDIAL ADIPOSE-TISSUE; ACTIVATED PROTEIN-KINASE; PLASMA-RENIN ACTIVITY; OXIDATIVE STRESS;

D O I：

10.1155/2012/349710

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The metabolic syndrome is a clustering of obesity, diabetes, hyperlipidemia, and hypertension that is occurring in increasing frequency across the global population. Although there is some controversy about its diagnostic criteria, oxidative stress, which is defined as imbalance between the production and inactivation of reactive oxygen species, has a major pathophysiological role in all the components of this disease. Oxidative stress and consequent inflammation induce insulin resistance, which likely links the various components of this disease. We briefly review the role of oxidative stress as a major component of the metabolic syndrome and then discuss the impact of exercise on these pathophysiological pathways. Included in this paper is the effect of exercise in reducing fat-induced inflammation, blood pressure, and improving muscular metabolism.

引用

页数：13

共 185 条

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