Human Milk Fatty Acid Composition of Allergic and Non-Allergic Mothers: The Ulm SPATZ Health Study

被引:3
作者
Siziba, Linda P. [1 ]
Lorenz, Leonie [2 ]
Stahl, Bernd [3 ,4 ]
Mank, Marko [3 ]
Marosvolgyi, Tamas [5 ]
Decsi, Tamas [5 ]
Rothenbacher, Dietrich [2 ]
Genuneit, Jon [1 ,2 ]
机构
[1] Univ Leipzig, Med Fac, Dept Pediat, Pediat Epidemiol, D-04103 Leipzig, Germany
[2] Ulm Univ, Inst Epidemiol & Med Biometry, D-89075 Ulm, Germany
[3] Danone Nutr Res, NL-3584 CT Utrecht, Netherlands
[4] Univ Utrecht, Utrecht Inst Pharmaceut Sci, Dept Chem Biol & Drug Discovery, NL-3584 CG Utrecht, Netherlands
[5] Univ Pecs, Med Sch, Dept Paediat, H-7623 Pecs, Hungary
关键词
human milk; fatty acids; maternal allergy; BREAST-MILK; ATOPIC MOTHERS; RISK;
D O I
10.3390/nu12061740
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The aim of this study was to determine the differences in human milk fatty acid composition in relation to maternal allergy within a large birth cohort study using statistical methods accounting for the correlations that exist in compositional data. We observed marginal differences in human milk fatty acid composition of allergic and non-allergic mothers. However, our results do not support the hypothesis that human milk fatty acid composition is influenced by allergy or that it differs between mothers with or without allergy. Observed differences in our results between transformed and untransformed fatty acid data call for re-evaluation of previous, as well as future, studies using statistical methods appropriate for compositionality of fatty acid data.
引用
收藏
页码:1 / 7
页数:8
相关论文
共 19 条
  • [1] Abnormal fatty acid profiles occur in atopic dermatitis but what do they mean?
    Calder, PC
    [J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2006, 36 (02) : 138 - 141
  • [2] Human milk polyunsaturated long-chain fatty acids and secretory immunoglobulin A antibodies and early childhood allergy
    Duchén, K
    Casas, R
    Fagerås-Böttcher, M
    Yu, G
    Björkstén, B
    [J]. PEDIATRIC ALLERGY AND IMMUNOLOGY, 2000, 11 (01) : 29 - 39
  • [3] Association of maternal allergy with human milk soluble CD14 and fatty acids, and early childhood atopic dermatitis
    Hua, Man-Chin
    Su, Hui-Min
    Kuo, Ming-Ling
    Chen, Chien-Chang
    Yao, Tsung-Chieh
    Tsai, Ming-Han
    Liao, Sui-Ling
    Lai, Shen-Hao
    Chiu, Chih-Yung
    Su, Kuan-Wen
    Chen, Li-Chen
    Yeh, Kuo-Wei
    Huang, Jing-Long
    [J]. PEDIATRIC ALLERGY AND IMMUNOLOGY, 2019, 30 (02) : 204 - 213
  • [4] Polyunsaturated fatty acids in maternal diet, breast milk, and serum lipid fatty acids of infants in relation to atopy
    Kankaanpää, P
    Nurmela, K
    Erkkilä, A
    Kalliomäki, M
    Holmberg-Marttila, D
    Salminen, S
    Isolauri, E
    [J]. ALLERGY, 2001, 56 (07) : 633 - 638
  • [5] Breast milk fatty acids, eicosanoids, and cytokines in mothers with and without allergic disease
    Laiho, K
    Lampi, AM
    Hämäläinen, M
    Moilanen, E
    Piironen, V
    Arvola, T
    Syrjänen, S
    Isolauri, E
    [J]. PEDIATRIC RESEARCH, 2003, 53 (04) : 642 - 647
  • [6] Genetic variants in the FADS gene cluster are associated with arachidonic acid concentrations of human breast milk at 1.5 and 6 mo postpartum and influence the course of milk dodecanoic, tetracosenoic, and trans-9-octadecenoic acid concentrations over the duration of lactation
    Lattka, Eva
    Rzehak, Peter
    Szabo, Eva
    Jakobik, Viktoria
    Weck, Melanie
    Weyermann, Maria
    Grallert, Harald
    Rothenbacher, Dietrich
    Heinrich, Joachim
    Brenner, Hermann
    Decsi, Tamas
    Illig, Thomas
    Koletzko, Berthold
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2011, 93 (02) : 382 - 391
  • [7] Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism
    Lattka, Eva
    Illig, Thomas
    Koletzko, Berthold
    Heinrich, Joachim
    [J]. CURRENT OPINION IN LIPIDOLOGY, 2010, 21 (01) : 64 - 69
  • [8] Fatty acid composition of human milk in atopic Danish mothers
    Lauritzen, Lotte
    Halkjaer, Liselotte Brydensholt
    Mikkelsen, Tina B.
    Olsen, Sjurdur F.
    Michaelsen, Kim F.
    Loland, Lotte
    Bisgaard, Hans
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2006, 84 (01) : 190 - 196
  • [9] What is the proper way to apply the multiple comparison test?
    Lee, Sangseok
    Lee, Dong Kyu
    [J]. KOREAN JOURNAL OF ANESTHESIOLOGY, 2018, 71 (05) : 353 - 360
  • [10] Changing Societal and Lifestyle Factors and Breastfeeding Patterns Over Time
    Logan, Chad
    Zittel, Tatjana
    Striebel, Stefanie
    Reister, Frank
    Brenner, Hermann
    Rothenbacher, Dietrich
    Genuneit, Jon
    [J]. PEDIATRICS, 2016, 137 (05)