Novel fragmentation reactions of bafilomycin A(1)

被引：7

作者：

Gatti, PA ^{[1
]}

Gagliardi, S ^{[1
]}

Cerri, A ^{[1
]}

Farina, C ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM SPA,I-20021 BARANZATE,MILANO,ITALY

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 39期

关键词：

D O I：

10.1016/S0040-4039(97)01629-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two novel fragmentations of the skeletal back bone of bafilomycin A(1) are reported. These reactions occur under mild conditions and afford new bafilomycin analogues lacking 4 and 8 carbon atoms of the tetrahydropyran ring, respectively. (C) 1997 Elsevier Science Ltd.

引用

页码：6949 / 6952

页数：4

共 6 条

[1]

BINDSEIL KU, 1994, LIEBIGS ANN CHEM, P305

[2] NOVEL LONG-RANGE H-1 AND C-13 NMR ISOTOPE EFFECTS TRANSMITTED VIA HYDROGEN-BONDS IN A MACROLIDE ANTIBIOTIC - BAFILOMYCIN-A1 [J].