Dietary Supplementation with Homoarginine Preserves Cardiac Function in a Murine Model of Post-Myocardial Infarction Heart Failure

被引：45

作者：

Atzler, Dorothee ^{[1
,2
,3
]}

McAndrew, Debra J. ^{[1
]}

Cordts, Kathrin ^{[4
,5
]}

Schneider, Jurgen E. ^{[1
]}

Zervou, Sevasti ^{[1
]}

Schwedhelm, Edzard ^{[4
,5
]}

Neubauer, Stefan ^{[1
]}

Lygate, Craig A. ^{[1
]}

机构：

[1] Univ Oxford, Radcliffe Dept Med, Div Cardiovasc Med, Oxford, England

[2] Ludwig Maximilians Univ Munchen, Inst Stroke & Dementia Res, Div Vasc Biol, Munich, Germany

[3] Ludwig Maximilians Univ Munchen, Deutsch Zentrum Herz Kreislauf Forsch eV, Partner Site Munich Heart Alliance, Inst Cardiovasc Prevent, Munich, Germany

[4] Univ Med Ctr Hamburg Eppendorf, Dept Clin Pharmacol & Toxicol, Hamburg, Germany

[5] Deutsch Zentrum Herz Kreislauf Forsch eV, Partner Site Hamburg Kiel Lubeck, Berlin, Germany

来源：

CIRCULATION | 2017年 / 135卷 / 04期

基金：

英国惠康基金;

关键词：

arginine; cardiovascular disease prevention; homoarginine; post-myocardial infarction heart failure;

D O I：

10.1161/CIRCULATIONAHA.116.025673

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：400 / 402

页数：3

共 5 条

[1] Oral supplementation with L-homoarginine in young volunteers [J].

Atzler, Dorothee ;

Schoenhoff, Mirjam ;

Cordts, Kathrin ;

Ortland, Imke ;

Hoppe, Julia ;

Hummel, Friedhelm C. ;

Gerloff, Christian ;

Jaehde, Ulrich ;

Jagodzinski, Annika ;

Boeger, Rainer H. ;

Choe, Chi-un ;

Schwedhelm, Edzard .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2016, 82 (06) :1477-1485

[2] L-Homoarginine and cardiovascular disease [J].

Atzler, Dorothee ;

Schwedhelm, Edzard ;

Choe, Chi-un .

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2015, 18 (01) :83-88

[3] Homoarginine Levels Are Regulated by L-Arginine: Glycine Amidinotransferase and Affect Stroke Outcome Results From Human and Murine Studies [J].

Choe, Chi-un ;

Atzler, Dorothee ;

Wild, Philipp S. ;

Carter, Angela M. ;

Boeger, Rainer H. ;

Ojeda, Francisco ;

Simova, Olga ;

Stockebrand, Malte ;

Lackner, Karl ;

Nabuurs, Christine ;

Marescau, Bart ;

Streichert, Thomas ;

Mueller, Christian ;

Lueneburg, Nicole ;

De Deyn, Peter P. ;

Benndorf, Ralf A. ;

Baldus, Stephan ;

Gerloff, Christian ;

Blankenberg, Stefan ;

Heerschap, Arend ;

Grant, Peter J. ;

Magnus, Tim ;

Zeller, Tanja ;

Isbrandt, Dirk ;

Schwedhelm, Edzard .

CIRCULATION, 2013, 128 (13) :1451-1461

[4] Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction [J].

Lygate, Craig A. ;

Bohl, Steffen ;

ten Hove, Michiel ;

Faller, Kiterie M. E. ;

Ostrowski, Philip J. ;

Zervou, Sevasti ;

Medway, Debra J. ;

Aksentijevic, Dunja ;

Sebag-Montefiore, Liam ;

Wallis, Julie ;

Clarke, Kieran ;

Watkins, Hugh ;

Schneider, Juergen E. ;

Neubauer, Stefan .

CARDIOVASCULAR RESEARCH, 2012, 96 (03) :466-475

[5] Homoarginine in the renal and cardiovascular systems [J].

Pilz, Stefan ;

Meinitzer, Andreas ;

Gaksch, Martin ;

Gruebler, Martin ;

Verheyen, Nicolas ;

Drechsler, Christiane ;

Hartaigh, Briain O. ;

Lang, Florian ;

Alesutan, Ioana ;

Voelkl, Jakob ;

Maerz, Winfried ;

Tomaschitz, Andreas .

AMINO ACIDS, 2015, 47 (09) :1703-1713

← 1 →