The role of Fluorine-18-Fluorodeoxyglucose positron emission tomography in staging and restaging of patients with osteosarcoma

被引：48

作者：

Quartuccio, Natale ^{[1
]}

Treglia, Giorgio ^{[2
,3
]}

Salsano, Marco ^{[4
]}

Mattoli, Maria Vittoria ^{[5
]}

Muoio, Barbara ^{[6
]}

Piccardo, Arnoldo ^{[7
]}

Lopci, Egesta ^{[8
]}

Cistaro, Angelina ^{[9
]}

机构：

[1] Univ Messina, Dept Radiol Sci, Nucl Med Unit, Messina, Italy

[2] Oncol Inst Southern Switzerland, Dept Nucl Med, Bellinzona, Switzerland

[3] Oncol Inst Southern Switzerland, PET CT Ctr, Bellinzona, Switzerland

[4] Univ Cattolica Sacro Cuore, Inst Radiol, I-00168 Rome, Italy

[5] Univ Cattolica Sacro Cuore, Inst Nucl Med, I-00168 Rome, Italy

[6] Univ Cattolica Sacro Cuore, Sch Med, I-00168 Rome, Italy

[7] Galliera Hosp, Nucl Med Unit, Genoa, Italy

[8] Humanitas Hosp, Nucl Med Unit, Milan, Italy

[9] Euromedic Inc, Positron Emiss Tomog Ctr IRMET, Turin, Italy

来源：

RADIOLOGY AND ONCOLOGY | 2013年 / 47卷 / 02期

关键词：

osteosarcoma; bone sarcoma; F-18-Fluorodeoxyglucose; PET/CT; positron emission tomography; HIGH-GRADE OSTEOSARCOMA; STUDY-GROUP PROTOCOLS; PRIMARY BONE-TUMORS; FDG-PET; PULMONARY METASTASES; F-18-FDG PET/CT; SARCOMA; CHEMOTHERAPY; EXTREMITIES; EXPERIENCE;

D O I：

10.2478/raon-2013-0017

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background. The objective of this study is to systematically review the role of positron emission tomography (PET) and PET/computed tomography (PET/CT) with Fluorine-18-Fluorodeoxyglucose (FDG) in patients with osteosarcoma (OS). Methods. A comprehensive literature search of published studies through October 10,h, 2012 in PubMed/MEDLINE, Embase and Scopus databases regarding whole-body FDG-PET and FDG-PET/CT in patients with OS was performed. Results. We identified 13 studies including 289 patients with OS. With regard to the staging and restaging of OS, the diagnostic performance of FDG-PET and PET/CT seem to be high; FDG-PET and PET/CT seem to be superior to bone scintigraphy and conventional imaging methods in detecting bone metastases; conversely, spiral CT seems to be superior to FDG-PET in detecting pulmonary metastases from OS Conclusions. Metabolic imaging may provide additional information in the evaluation of OS patients. The combination of FDG-PET or FDG-PET/CT with conventional imaging methods seems to be a valuable tool in the staging and restaging of OS and may have a relevant impact on the treatment planning.

引用

页码：97 / 102

页数：6

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