Simultaneous Occurrence of Guillain-Barre Syndrome in Three Members of the Same Family: A Case Report

被引：1

作者：

Ullah, Assam ^{[1
]}

Khan, Salman ^{[1
]}

Humayun, Omama ^{[1
]}

Ullah, Sana ^{[2
]}

Fatima, Noor ^{[3
]}

机构：

[1] Khyber Teaching Hosp, Internal Med, Peshawar, Pakistan

[2] Lady Reading Hosp, Dept Med, Peshawar, Pakistan

[3] Fatima Mem Hosp, Dept Med, Coll Med & Dent, Lahore, Pakistan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 09期

关键词：

sibling; autoimmune; genetic susceptibility; ascending paralysis; aman; familial; guillain-barre syndrome; CAMPYLOBACTER-JEJUNI INFECTION;

D O I：

10.7759/cureus.29356

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Guillain-Barre syndrome (GBS) is an autoimmune demyelinating disease that is usually triggered by an antecedent infection and is characterized by flaccid paralysis and hyporeflexia. Although a sporadic disease, a few cases of GBS have been reported in families, suggesting a genetic predisposition. Here, we present a case of simultaneous occurrence of GBS in three members of the same family, with two members having a preceding history of diarrhea. They were diagnosed via cerebrospinal fluid routine examination and nerve conduction study and responded to plasmapheresis. This suggests possible genetic susceptibility along with environmental triggers in the pathogenesis of GBS.

引用

页数：3

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