Human chorionic gonadotropin levels in early IVF/ICSI pregnancies are higher in singletons after single embryo transfer compared with singletons after double embryo transfer

被引：5

作者：

Delbaere, I. ^{[1
]}

Vansteelandt, S. ^{[2
]}

Gerris, J. ^{[1
]}

De Sutter, P. ^{[1
]}

De Bacquer, D. ^{[3
]}

Temmerman, M. ^{[1
]}

机构：

[1] Univ Ghent, Dept Obstet & Gynaecol, B-9000 Ghent, Belgium

[2] Univ Ghent, Dept Appl Math & Comp Sci, B-9000 Ghent, Belgium

[3] Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium

来源：

HUMAN REPRODUCTION | 2008年 / 23卷 / 11期

关键词：

hCG; implantation; SET; DET;

D O I：

10.1093/humrep/den289

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

BACKGROUND: The aim of this study is to assess differences in human chorionic gonadotropin (hCG) values between singleton IVF/ICSI pregnancies after elective single (eSET) versus double embryo transfer (DET). METHODS: This is a unicentre, retrospective, non-randomized study of women with eSET or DET in years 2000-2006, giving birth to a singleton child with a birthweight of at least 500 g (N = 790). These women had between 1 and 6 hCG assessments in our centre. Log hCG values from Days 15 to 35 after oocyte pick-up were compared between eSET and DET patients in a multivariate analysis. RESULTS: We compared log hCG values in 456 eSET patients with log hCG values in 334 DET patients. Log hCG values were significantly higher after eSET than after DET from Day 15 until Day 35 after oocyte pick-up (P < 0.001). CONCLUSION: The lower hCG values in early pregnancy are possibly due to a delay in implantation when two embryos are transferred and one of them does not implant, but the exact mechanism is unknown.

引用

页码：2421 / 2426

页数：6

共 21 条

[1] Human chorionic gonadotrophin concentrations in early pregnancy after in-vitro fertilization [J].