Drug discovery research in Ghana, challenges, current efforts, and the way forward

被引：9

作者：

Amewu, Richard Kwamla ^{[1
]}

Amoateng, Patrick ^{[2
]}

Arthur, Patrick Kobina ^{[3
]}

Asare, Prince ^{[4
]}

Asiamah, Isaac ^{[5
]}

Boamah, Daniel ^{[6
]}

Otchere, Isaac Darko ^{[4
]}

Amengor, Cedric Dzidzor ^{[7
]}

Ekuadzi, Edmund ^{[8
]}

Chibale, Kelly ^{[9
]}

Farrell, Susan Jane ^{[10
]}

Appiah-Oppong, Regina ^{[11
]}

Osei-Safo, Dorcas ^{[1
]}

Read, Kevin David ^{[10
]}

Hugh Gilbert, Ian ^{[10
]}

Yeboah-Manu, Dorothy ^{[4
]}

机构：

[1] Univ Ghana, Dept Chem, Legon Accra, Ghana

[2] Univ Ghana, Sch Pharm, Dept Pharmacol & Toxicol, Coll Hlth Sci, Legon Accra, Ghana

[3] Univ Ghana, Dept Biochem Cell & Mol Biol, Legon Accra, Ghana

[4] Univ Ghana, Noguchi Mem Inst Med Res, Dept Bacteriol, Legon, Ghana

[5] Univ Cape Coast, Sch Phys Sci, Dept Chem, Cape Coast, Ghana

[6] Ctr Plant Med, Dept Microbiol, Mampong Akuapem, Ghana

[7] Univ Hlth & Allied Sci, Sch Pharm, Dept Pharmaceut Chem, Ho, Ghana

[8] Kwame Nkrumah Univ Sci & Technol KNUST, Fac Pharm & Pharmaceut Sci, Dept Pharmacognosy, Kumasi, Ghana

[9] Univ Cape Town UCT, Holist Drug Discovery & Dev H3D Ctr, Rondebosch, South Africa

[10] Univ Dundee, Div Biol Chem & Drug Discovery, Wellcome Ctr AntiInfect Res WCAIR, Dundee, Scotland

[11] Univ Ghana, Noguchi Mem Inst Med Res, Dept Clin Pathol, Legon, Ghana

来源：

PLOS NEGLECTED TROPICAL DISEASES | 2022年 / 16卷 / 09期

基金：

英国惠康基金;

关键词：

STEM BARK; ALKALOIDS;

D O I：

10.1371/journal.pntd.0010645

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We have a long-term vision to develop drug discovery research capacity within Ghana, to tackle unmet medical needs in Ghana and the wider West African region. However, there are several issues and challenges that need to be overcome to enable this vision, including training, human resource, equipment, infrastructure, procurement, and logistics. We discuss these challenges from the context of Ghana in this review. An important development is the universities and research centres within Ghana working together to address some of these challenges. Therefore, while there is a long way to go to fully accomplish our vision, there are encouraging signs.

引用

页数：9

共 21 条

[1] COMPARATIVE-EXAMINATION OF 2 ZANTHOXYLUM BENZOPHENANTHRIDINE ALKALOIDS FOR CARDIOVASCULAR EFFECTS IN RABBITS [J].