Studies on serological cross-reaction of Neospora caninum with Toxoplasma gondii and Hammondia heydorni

被引：40

作者：

Nishikawa, Y ^{[1
]}

Claveria, FG ^{[1
]}

Fujisaki, K ^{[1
]}

Nagasawa, H ^{[1
]}

机构：

[1] Obihiro Univ Agr & Vet Med, Natl Res Ctr Protozoan Dis, Obihiro, Hokkaido 0808555, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2002年 / 64卷 / 02期

关键词：

ELISA; Neospora caninum;

D O I：

10.1292/jvms.64.161

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The enzyme-linked immunosorbent assay (ELISA) was used to examine cross-reactivity of Neospora caninum with Toxoplasma gondii and Hammondia heydorni. Anti-T. gondii mouse and cat sera cross-reacted with N. caninum soluble antigen (NLA), but not with the recombinant surface antigen (NcSRS2). Anti-H. heydorni dog sera showed no cross-reactivity with either the NLA antigen or the NcSRS2. Lack of cross-reactivity between anti-H. heydorni sera and N. caninum antigens, and the cross-reactivity of anti-T. gondii sera with the NLA suggest that N. caninum has common antigens to T. gondii except for NcSRS2 based on serology. In light of several studies suggesting a closer relationship between N. caninum and H. heydorni than with T. gondii, examination of serological cross-reactivity with N. caninum may be necessary to further classify the parasites in addition to molecular and morphological studies and clarification of the life cycle.

引用

页码：161 / 164

页数：4

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