Conversion surgery for locally advanced malignant pleural mesothelioma

被引:0
作者
Terada, Yukihiro [1 ]
Isaka, Mitsuhiro [1 ]
Murakami, Haruyasu [2 ]
Kawata, Takuya [3 ]
Konno, Hayato [1 ]
Kojima, Hideaki [1 ]
Mizuno, Tetsuya [1 ]
Ohde, Yasuhisa [1 ]
机构
[1] Shizuoka Canc Ctr, Div Thorac Surg, Shimonagakubo 1007, Nagaizumi, Shizuoka 4118777, Japan
[2] Shizuoka Canc Ctr, Div Thorac Oncol, Shizuoka, Japan
[3] Shizuoka Canc Ctr, Div Pathol, Shizuoka, Japan
关键词
Malignant pleural mesothelioma; Conversion surgery; Locally advanced; Pleurectomy; decortication; Chemotherapy; PLEURECTOMY; MULTICENTER; SURVIVAL;
D O I
10.1007/s11748-020-01329-y
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Two women in their sixties were diagnosed with inoperable locally advanced epithelioid malignant pleural mesothelioma, c-stage IIIB. Post-chemotherapy, the tumors down-staged to yc-stage IA, and pleurectomy/decortication were performed. The pathological diagnoses were p-stages II and IA. One patient had tumor recurrence 6 months after surgery; she is currently undergoing fourth-line chemotherapy and is alive 30 months postoperatively. The second patient had tumor recurrence 4 months after surgery and died 2 months later. Conversion surgery for advanced malignant mesothelioma does not improve progression-free survival but might have a chance to extend overall survival in selected patients without deteriorating performance status.
引用
收藏
页码:1547 / 1550
页数:4
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