Atopic disorders: a default pathway in the absence of infection?

被引：72

作者：

Erb, KJ ^{[1
]}

机构：

[1] Univ Wurzburg, Zentrum Infekt Forsch, D-97070 Wurzburg, Germany

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 07期

关键词：

D O I：

10.1016/S0167-5699(99)01475-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Atopic disorders, such as asthma, are increasingly prevalent in the developed world. Recent epidemiological and experimental data suggest that some infectious diseases prevalent in the developing nations can inhibit the development of allergic disorders. Here, Klaus Erb reviews the data and presents a model showing how a steady decline of infections diseases could account for an increase in atopic disorders.

引用

页码：317 / 322

页数：6

共 57 条

[1] Functional diversity of helper T lymphocytes
Abbas, AK
Murphy, KM
Sher, A
[J]. NATURE, 1996, 383 (6603) : 787 - 793
[2] Ballas ZK, 1996, J IMMUNOL, V157, P1840
[3] IgE, allergies and helminth parasites: A new perspective on an old conundrum
Bell, RG
[J]. IMMUNOLOGY AND CELL BIOLOGY, 1996, 74 (04) : 337 - 345
[4] BROBOCK L, 1994, CLIN EXP ALLERGY, V26, P621
[5] Relationship between allergic manifestations and Toxocara seropositivity: A cross-sectional study among elementary school children
Buijs, J
Borsboom, G
Renting, M
Hilgersom, WJA
vanWieringen, JC
Jansen, G
Neijens, J
[J]. EUROPEAN RESPIRATORY JOURNAL, 1997, 10 (07) : 1467 - 1475
[6] ASSOCIATION OF ASTHMA WITH SERUM IGE LEVELS AND SKIN-TEST REACTIVITY TO ALLERGENS
BURROWS, B
MARTINEZ, FD
HALONEN, M
BARBEE, RA
CLINE, MG
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1989, 320 (05) : 271 - 277
[7] Immunology - Asthma: An epidemic in the absence of infection?
Cookson, WOCM
Moffatt, MF
[J]. SCIENCE, 1997, 275 (5296) : 41 - 42
[8] Coyle AJ, 1998, EUR J IMMUNOL, V28, P2640, DOI 10.1002/(SICI)1521-4141(199809)28:09&lt
[9] 2640::AID-IMMU2640&gt
[10] 3.0.CO

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