Getting to the "Heart" of Cardiac Disease by Decreasing Mitochondrial Iron

被引:29
作者
Chang, Hsiang-Chun [1 ]
Shapiro, Jason S. [1 ]
Ardehali, Hossein [1 ]
机构
[1] Northwestern Univ, Feinberg Cardiovasc Res Inst, 303 E Chicago Ave,Tarry 14-733, Chicago, IL 60611 USA
关键词
anemia; heart failure; iron; mitochondria; myocardial reperfusion; FERRIC CARBOXYMALTOSE; DEFICIENCY; FAILURE; CHELATION;
D O I
10.1161/CIRCRESAHA.116.309746
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Iron chelation rather than supplementation would be beneficial to patients with heart diseases. More effort should be devoted to the development of iron chelators that could target mitochondrial iron.
引用
收藏
页码:1164 / 1166
页数:3
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