Biomimetic sensing based on chemically induced assembly of a signaling DNA aptamer on a fluid bilayer membrane

被引：31

作者：

Dave, Neeshma ^{[1
]}

Liu, Juewen ^{[1
]}

机构：

[1] Univ Waterloo, Dept Chem, Waterloo Inst Nanotechnol, Waterloo, ON N2L 3G1, Canada

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 31期

基金：

加拿大自然科学与工程研究理事会;

关键词：

GOLD NANOPARTICLES; ELECTROCHEMICAL BIOSENSORS; LIPID-MEMBRANES; ANCHORED DNA; SENSORS; ADENOSINE; LIPOSOMES; BINDING; SYSTEMS; DESIGN;

D O I：

10.1039/c2cc00070a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The adenosine aptamer was split into two halves and linked to a fluid liposome surface; addition of adenosine resulted in aptamer assembly, which did not occur if the split aptamer was attached to silica nanoparticles, demonstrating the feasibility of using aptamer probes to study diffusion within lipid membranes.

引用

页码：3718 / 3720

页数：3

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