CLIMB (the Cloud Infrastructure for Microbial Bioinformatics): an online resource for the medical microbiology community

被引：124

作者：

Connor, Thomas R. ^{[1
]}

Loman, Nicholas J. ^{[2
]}

Thompson, Simon ^{[3
]}

Smith, Andy ^{[2
]}

Southgate, Joel ^{[1
]}

Poplawski, Radoslaw ^{[2
,3
]}

Bull, Matthew J. ^{[1
]}

Richardson, Emily ^{[2
]}

Ismail, Matthew ^{[4
]}

Elwood-Thompson, Simon ^{[5
]}

Kitchen, Christine ^{[6
]}

Guest, Martyn ^{[6
]}

Bakke, Marius ^{[7
]}

Sheppard, Samuel K. ^{[8
]}

Pallen, Mark J. ^{[7
]}

机构：

[1] Cardiff Univ, Sch Biosci, Sir Martin Evans Bldg, Cardiff CF10 2AX, S Glam, Wales

[2] Univ Birmingham, Inst Microbiol & Infect, Birmingham B15 2TT, W Midlands, England

[3] Univ Birmingham, IT Serv Res Comp, Birmingham B15 2TT, W Midlands, England

[4] Univ Warwick, Ctr Sci Comp, Coventry CV4 7AL, W Midlands, England

[5] Swansea Univ, Coll Med, Swansea, W Glam, Wales

[6] Cardiff Univ, Adv Res Comp Cardiff ARCCA, Cardiff, S Glam, Wales

[7] Univ Warwick, Warwick Med Sch, Microbiol & Infect Unit, Coventry, W Midlands, England

[8] Univ Bath, Dept Biol & Biochem, Milner Ctr Evolut, Bath BA2 7AY, Avon, England

来源：

MICROBIAL GENOMICS | 2016年 / 2卷 / 09期

基金：

英国生物技术与生命科学研究理事会;

关键词：

cloud computing; bioinformatics; infrastructure; metagenomics; population genomics; virtual laboratory;

D O I：

10.1099/mgen.0.000086

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The increasing availability and decreasing cost of high-throughput sequencing has transformed academic medical microbiology, delivering an explosion in available genomes while also driving advances in bioinformatics. However, many microbiologists are unable to exploit the resulting large genomics datasets because they do not have access to relevant computational resources and to an appropriate bioinformatics infrastructure. Here, we present the Cloud Infrastructure for Microbial Bioinformatics (CLIMB) facility, a shared computing infrastructure that has been designed from the ground up to provide an environment where microbiologists can share and reuse methods and data.

引用

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